1. Gene
  2. Adamts19 - a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 19 Gene

Adamts19 - a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 19 Gene

Mus musculus

Also known as 4831407I23Rik; D230034E10Rik

Gene ID: 240322 | Gene type: protein coding

About Adamts19

Summary

This gene encodes a member of "a disintegrin and metalloproteinase with thrombospondin motifs" (ADAMTS) family of multi-domain matrix-associated metalloendopeptidases that have diverse roles in tissue morphogenesis and pathophysiological remodeling, in inflammation and in vascular biology. This gene is predominantly expressed in the ovary with lower levels of expression observed in kidney, heart, skeletal muscle, lung and testis. The encoded preproprotein undergoes proteolytic processing to generate an active protease. [provided by RefSeq, Jul 2016]

Adamts19 Products(1)

mRNA Protein Name
NM_175506.4 NP_780715.1 A disintegrin and metalloproteinase with thrombospondin motifs 19 preproprotein
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in aortic valve morphogenesis IMP
IMP: Inferred from mutant phenotype
31844321 MGI
involved in collagen fibril organization IMP
IMP: Inferred from mutant phenotype
31844321 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

A disintegrin and metalloproteinase with thrombospondin motifs 19

a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 19

Orthologs Information

Species Symbol Source ID
Homo sapiens Adamts19 NCBI NCBI:171019