2. Gene
  3. Adam23 - a disintegrin and metallopeptidase domain 23 Gene

Adam23 - a disintegrin and metallopeptidase domain 23 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as MDC3

Gene ID: 23792 | Gene type: protein coding

About Adam23

Summary

This gene encodes a member of the disintegrin family of membrane-anchored proteins that play a role in diverse biological processes such as brain development, fertilization, tumor development and inflammation. The encoded protein undergoes proteolytic processing to generate a mature polypeptide comprised of an inactive metalloprotease and disintegrin domains. Transgenic disruption of this gene in mice results in postnatal neurological defects including tremor and ataxia resulting in death by 2 weeks of age. [provided by RefSeq, Sep 2015]

Adam23 Products(1)

mRNA Protein Name
NM_011780.3 NP_035910.1 disintegrin and metalloproteinase domain-containing protein 23 preproprotein
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
16990550 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: Inferred from expression pattern
20439489 MGI
Cellular Component GO Annotation Evidence Reference Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
20133599 MGI
is active in presynaptic membrane IDA
IDA: Inferred from direct assay
20133599 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

disintegrin and metalloproteinase domain-containing protein 23

a disintegrin and metalloprotease domain 23

metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00279 ADAM23 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19761 Adam23 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26258 Adam23 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Adam23 NCBI NCBI:8745