2. Gene
  3. Gckr - glucokinase regulatory protein Gene

Gckr - glucokinase regulatory protein Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as GKRP

Gene ID: 231103 | Gene type: protein coding

About Gckr

Summary

Predicted to enable several functions, including carbohydrate binding activity; enzyme inhibitor activity; and fructose-6-phosphate binding activity. Involved in positive regulation of Glucokinase activity. Acts upstream of or within cellular glucose homeostasis; negative regulation of Glucokinase activity; and protein import into nucleus. Located in nucleus. Is expressed in diencephalon lateral wall mantle layer; liver left lobe; liver right lobe; midbrain mantle layer; and retina. Human ortholog(s) of this gene implicated in end stage renal disease and type 2 diabetes mellitus. Orthologous to human GCKR (Glucokinase regulator). [provided by Alliance of Genome Resources, Apr 2022]

Gckr Products(2)

mRNA Protein Name
NM_001374741.1 NP_001361670.1 glucokinase regulatory protein isoform 1
NM_144909.2 NP_659158.1 glucokinase regulatory protein isoform 2
Protein Preferred Names Protein Names

glucokinase regulatory protein

glucokinase regulator

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05332 GCKR Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS19603 Gckr Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26099 Gckr Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gckr NCBI NCBI:2646