2. Gene
  3. ENDOD1 - endonuclease domain containing 1 Gene

ENDOD1 - endonuclease domain containing 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 23052 | Gene type: protein coding

About ENDOD1

Cytogenetic location: 11q21 Genomic coordinates (GRCh38): 11:95,089,846-95,132,645 (from NCBI)

This gene has 1 transcript (splice variant) and 172 orthologues. Ubiquitous expression in prostate (RPKM 33.4), brain (RPKM 27.7) and 24 other tissues.

Summary

Predicted to enable Endonuclease activity; metal ion binding activity; and nucleic acid binding activity. Predicted to be involved in nucleic acid phosphodiester bond hydrolysis. Located in extracellular exosome and membrane. [provided by Alliance of Genome Resources, Apr 2022]

ENDOD1 Products(1)

mRNA Protein Name
NM_015036.3 NP_055851.1 endonuclease domain-containing 1 protein precursor
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ENDOD1 Protein Structure

Endonuclease_NS

Endonuclease_NS: DNA/RNA non-specific endonuclease (63 - 230)

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  • 500 a.a.
Protein Preferred Names Protein Names

endonuclease domain-containing 1 protein

ENDOD1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
ENDOD1 O94919 VSNL1 Homo sapiens P62760
Validated Y2H
32296183
Intra
ENDOD1 O94919 VSNL1 Homo sapiens P62760
Y2H Prey Pooling
32296183
Intra
ENDOD1 O94919 VSNL1 Homo sapiens P62760
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04370 ENDOD1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21123 Endod1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27642 Endod1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris ENDOD1 VGNC VGNC:52258
Felis catus ENDOD1 VGNC VGNC:61858
Macaca mulatta ENDOD1 VGNC VGNC:100925
Bos taurus ENDOD1 VGNC VGNC:28490
Rattus norvegicus ENDOD1 RGD RGD:1310444
Mus musculus ENDOD1 MGD MGI:1919196