2. Gene
  3. Srsf7 - serine and arginine-rich splicing factor 7 Gene

Srsf7 - serine and arginine-rich splicing factor 7 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 9G8; 35kDa; NX-96; Sfrs7; 9430065L19Rik

Gene ID: 225027 | Gene type: protein coding

About Srsf7

Summary

The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding Other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Multiple protein-coding and non-protein-coding transcript variants have been found for this gene. [provided by RefSeq, Apr 2022]

Srsf7 Products(6)

mRNA Protein Name
NM_001195485.1 NP_001182414.1 serine/arginine-rich splicing factor 7 isoform 2
NM_001195486.1 NP_001182415.1 serine/arginine-rich splicing factor 7 isoform 3
NM_001195487.1 NP_001182416.1 serine/arginine-rich splicing factor 7 isoform 4
NM_001360435.1 NP_001347364.1 serine/arginine-rich splicing factor 7 isoform 6
NM_001404106.1 NP_001391035.1 serine/arginine-rich splicing factor 7 isoform 7
NM_146083.2 NP_666195.1 serine/arginine-rich splicing factor 7 isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
8871564 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: Inferred from expression pattern
20439489 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

serine/arginine-rich splicing factor 7

splicing factor, arginine/serine-rich 7

Srsf7 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
Srsf7 Q8BL97 Tra2a Mus musculus Q6PFR5
Pull Down
16249178
Intra
Srsf7 Q8BL97 Tra2a Mus musculus Q6PFR5
Y2H
16249178
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13798 SRSF7 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS19484 Srsf7 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25977 Srsf7 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Srsf7 NCBI NCBI:6432