Baz1b - bromodomain adjacent to zinc finger domain, 1B Gene

Mus musculus

Also known as WSTF; Wbscr9

Gene ID: 22385 | Gene type: protein coding

About Baz1b

Summary

Enables histone binding activity. Acts upstream of or within chromatin assembly or disassembly and chromatin remodeling. Located in condensed chromosome; nucleus; and pericentric heterochromatin. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; lung mesenchyme; and retina. Used to study Williams-Beuren syndrome. Orthologous to human BAZ1B (bromodomain adjacent to zinc finger domain 1B). [provided by Alliance of Genome Resources, Apr 2022]

Baz1b Products(1)

mRNA	Protein	Name
NM_011714.2	NP_035844.2	tyrosine-protein kinase BAZ1B

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables histone binding	IPI IPI: Inferred from physical interaction	19092802	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	11980720	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within chromatin organization	IDA IDA: Inferred from direct assay	11980720	MGI
acts upstream of or within chromatin remodeling	IDA IDA: Inferred from direct assay	11980720	MGI
involved in chromatin remodeling	IDA IDA: Inferred from direct assay	11980720	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in condensed chromosome	IDA IDA: Inferred from direct assay	11980720	MGI
located in nucleus	IDA IDA: Inferred from direct assay	11980720	MGI
located in pericentric heterochromatin	IDA IDA: Inferred from direct assay	11980720	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

tyrosine-protein kinase BAZ1B

Williams-Beuren syndrome chromosome region 9 homolog	bromodomain adjacent to zinc finger domain protein 1B
bromodomain adjacent to zinc finger domain, 1B	Williams-Beuren syndrome chromosome region 9 homolog
williams syndrome transcription factor homol

Baz1b Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	Baz1b	Q9Z277	Smarca5	Mus musculus	Q91ZW3	Anti Bait CoIP	11980720

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01378	BAZ1B Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS22404	Baz1b Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Baz1b	NCBI	NCBI:9031

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