Eif3l - eukaryotic translation initiation factor 3, subunit L Gene

Mus musculus

Also known as PAF67; D15N1e; Eif3ip; Eif3eip; HSP-66Y; Eif3s6ip; 0610011H21Rik

Gene ID: 223691 | Gene type: protein coding

About Eif3l

Summary

Contributes to translation initiation factor activity. Involved in translational initiation. Located in fibrillar center and nucleoplasm. Part of eukaryotic translation initiation factor 3 complex. Is expressed in thymus primordium. Orthologous to human EIF3L (eukaryotic translation initiation factor 3 subunit L). [provided by Alliance of Genome Resources, Apr 2022]

Eif3l Products(1)

mRNA	Protein	Name
NM_145139.2	NP_660121.2	eukaryotic translation initiation factor 3 subunit L

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	11592397	MGI
contributes to translation initiation factor activity	IDA IDA: Inferred from direct assay	17581632	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in translational initiation	IDA IDA: Inferred from direct assay	17581632	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
part of eukaryotic translation initiation factor 3 complex	IDA IDA: Inferred from direct assay	17581632	MGI
located in fibrillar center	IDA IDA: Inferred from direct assay	11592397	MGI
located in nucleolus	IDA IDA: Inferred from direct assay	11592397	MGI
located in nucleoplasm	IDA IDA: Inferred from direct assay	11592397	MGI
is active in synapse	EXP EXP: Inferred from Experiment	25211037	MGI
is active in synapse	IDA IDA: Inferred from direct assay	25211037	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

eukaryotic translation initiation factor 3 subunit L

66 kDa tyrosine-rich heat shock protein	67 kDa polymerase-associated factor
eukaryotic translation initiation factor 3 subunit 6-interacting protein	eukaryotic translation initiation factor 3 subunit E-interacting protein

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04268	EIF3L Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS21563	Eif3l Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Eif3l	NCBI	NCBI:51386

Name
Email *

	Sorry, but the email address you supplied was invalid.