2. Gene
  3. Ucp3 - uncoupling protein 3 (mitochondrial, proton carrier) Gene

Ucp3 - uncoupling protein 3 (mitochondrial, proton carrier) Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as UCP-3; Slc25a9

Gene ID: 22229 | Gene type: protein coding

About Ucp3

Summary

Enables Oxidative Phosphorylation uncoupler activity. Acts upstream of or within fatty acid metabolic process and response to superoxide. Located in mitochondrion. Is expressed in adipose tissue; heart; and skeletal muscle. Human ortholog(s) of this gene implicated in coronary restenosis; diabetic neuropathy; glucose metabolism disease (multiple); and obesity. Orthologous to human UCP3 (uncoupling protein 3). [provided by Alliance of Genome Resources, Apr 2022]

Ucp3 Products(1)

mRNA Protein Name
NM_009464.3 NP_033490.1 mitochondrial uncoupling protein 3
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
NOT enables oxidative phosphorylation uncoupler activity IMP
IMP: Inferred from mutant phenotype
11707458 MGI
enables oxidative phosphorylation uncoupler activity IMP
IMP: Inferred from mutant phenotype
10748195 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
26915802 MGI
enables proton transmembrane transporter activity IDA
IDA: Inferred from direct assay
29212043 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within fatty acid metabolic process IMP
IMP: Inferred from mutant phenotype
10748196 MGI
involved in lipid hydroperoxide transport IMP
IMP: Inferred from mutant phenotype
20363757 MGI
involved in proton transmembrane transport IDA
IDA: Inferred from direct assay
29212043 MGI
acts upstream of or within response to superoxide IMP
IMP: Inferred from mutant phenotype
11780125 MGI
Cellular Component GO Annotation Evidence Reference Source
located in mitochondrial inner membrane IDA
IDA: Inferred from direct assay
26915802 MGI
located in mitochondrion IMP
IMP: Inferred from mutant phenotype
11707458 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mitochondrial uncoupling protein 3

solute carrier family 25 member 9

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-117549 Ibrolipim Activator 99.48% Phase 2
Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15412 UCP3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20349 Ucp3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26858 Ucp3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ucp3 NCBI NCBI:7352