2. Gene
  3. Thbs4 - thrombospondin 4 Gene

Thbs4 - thrombospondin 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as TSP4

Gene ID: 21828 | Gene type: protein coding

About Thbs4

Summary

Predicted to enable several functions, including fibronectin binding activity; heparin binding activity; and laminin-1 binding activity. Involved in behavioral response to pain; regulation of tissue remodeling; and response to endoplasmic reticulum stress. Located in collagen-containing extracellular matrix; extracellular space; and sarcoplasmic reticulum. Is expressed in several structures, including brain; genitourinary system; gut; heart; and skeletal musculature. Orthologous to human THBS4 (thrombospondin 4). [provided by Alliance of Genome Resources, Apr 2022]

Thbs4 Products(1)

mRNA Protein Name
NM_011582.3 NP_035712.1 thrombospondin-4 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
22682248 MGI
Biological Process GO Annotation Evidence Reference Source
involved in behavioral response to pain IMP
IMP: Inferred from mutant phenotype
22745497 MGI
involved in regulation of tissue remodeling IMP
IMP: Inferred from mutant phenotype
22362893 MGI
involved in response to endoplasmic reticulum stress IMP
IMP: Inferred from mutant phenotype
22682248 MGI
Cellular Component GO Annotation Evidence Reference Source
located in collagen-containing extracellular matrix IDA
IDA: Inferred from direct assay
22362893 MGI
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
22682248 MGI
located in extracellular space IDA
IDA: Inferred from direct assay
22682248 MGI
located in sarcoplasmic reticulum IDA
IDA: Inferred from direct assay
22682248 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

thrombospondin-4

Thbs4 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
Thbs4 Q9Z1T2 Atf6 Mus musculus F6VAN0
Anti Bait CoIP
22682248
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14482 THBS4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19485 Thbs4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25979 Thbs4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Thbs4 NCBI NCBI:7060