Ptpdc1 - protein tyrosine phosphatase domain containing 1 Gene

Mus musculus

Also known as Naa-1; Ptpcd1

Gene ID: 218232 | Gene type: protein coding

About Ptpdc1

Summary

The protein encoded by this gene is a centrosomal mitotic Phosphatase. This protein has been implicated in centrosomal duplication and cytokinesis. In addition, knockdown of expression levels in non-cycling cells results in extra long cilia, suggesting that this protein may function in regulating cilia length independent of a function in cell cycle control. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2014]

Ptpdc1 Products(3)

mRNA	Protein	Name
NM_001301781.1	NP_001288710.1	protein tyrosine phosphatase domain-containing protein 1 isoform 1
NM_001374755.1	NP_001361684.1	protein tyrosine phosphatase domain-containing protein 1 isoform 3
NM_207232.2	NP_997115.1	protein tyrosine phosphatase domain-containing protein 1 isoform 2

Gene Ontology

Biological Process

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within cilium assembly	IMP IMP: Inferred from mutant phenotype	21289087	MGI
acts upstream of or within smoothened signaling pathway	IMP IMP: Inferred from mutant phenotype	21289087	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

protein tyrosine phosphatase domain-containing protein 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11413	PTPDC1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS21917	Ptpdc1 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Ptpdc1	NCBI	NCBI:138639

Name
Email *

	Sorry, but the email address you supplied was invalid.