2. Gene
  3. Eif5 - eukaryotic translation initiation factor 5 Gene

Eif5 - eukaryotic translation initiation factor 5 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as D12Ertd549e; 2810011H21Rik

Gene ID: 217869 | Gene type: protein coding

About Eif5

Summary

Predicted to enable GDP-dissociation inhibitor activity; eukaryotic initiation factor eIF2 binding activity; and translation initiation factor activity. Predicted to be involved in activation of GTPase activity; cytoplasmic translational initiation; and regulation of translational initiation. Predicted to act upstream of or within translation. Predicted to be located in cytoplasm and plasma membrane. Predicted to be active in cytosol. Is expressed in several structures, including central nervous system; dorsal root ganglion; ear; genitourinary system; and retina nuclear layer. Orthologous to human EIF5 (eukaryotic translation initiation factor 5). [provided by Alliance of Genome Resources, Apr 2022]

Eif5 Products(2)

mRNA Protein Name
NM_173363.5 NP_775539.1 eukaryotic translation initiation factor 5
NM_178041.2 NP_829887.1 eukaryotic translation initiation factor 5
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
is active in synapse EXP
EXP: Inferred from Experiment
25211037 MGI
is active in synapse IDA
IDA: Inferred from direct assay
25211037 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

eukaryotic translation initiation factor 5

eIF-5

Related Agents

Pre-clinical Phase
Bioactive Molecules (14)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-111522 RK-9123016 Inhibitor 99.02% Unkown
HY-121722 Deoxyhypusine / Unkown
HY-122039 Hypusine dihydrochloride / Unkown
HY-RS04285 EIF5 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS04286 EIF5A Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS04287 EIF5A2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS04288 EIF5B Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS18929 Eif5 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS19060 Eif5a2 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS19678 Eif5a Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS22482 Eif5b Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25419 Eif5 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25550 Eif5a2 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26171 Eif5a Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Eif5 NCBI NCBI:1983