2. Gene
  3. Nags - N-acetylglutamate synthase Gene

Nags - N-acetylglutamate synthase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as argA; 1700120E20Rik

Gene ID: 217214 | Gene type: protein coding

About Nags

Summary

Enables acetyl-CoA:L-glutamate N-acetyltransferase activity. Acts upstream of or within glutamate metabolic process. Located in mitochondrion. Human ortholog(s) of this gene implicated in N-acetylglutamate synthase deficiency and amino acid metabolic disorder. Orthologous to human NAGS (N-acetylglutamate synthase). [provided by Alliance of Genome Resources, Apr 2022]

Nags Products(1)

mRNA Protein Name
NM_145829.2 NP_665828.1 N-acetylglutamate synthase, mitochondrial precursor
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables L-glutamate N-acetyltransferase activity IDA
IDA: Inferred from direct assay
12049647 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within glutamate metabolic process IDA
IDA: Inferred from direct assay
12049647 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

N-acetylglutamate synthase, mitochondrial

amino-acid N-acetyltransferase

amino-acid acetyltransferase

Related Agents

Approval
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B0711 Carglumic Acid Activator 99.90% Yes
HY-B0711R Carglumic Acid (Standard) Activator / Unkown
Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-132604 Fazirsiran / Phase 3
Pre-clinical Phase
Bioactive Molecules (12)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-103332 N-Arachidonylglycine Inhibitor 98.90% Unkown
HY-139431 NAG-thiazoline Inhibitor 98.08% Unkown
HY-132604A Fazirsiran sodium 93.86% Unkown
HY-103332S N-Arachidonylglycine-d8 Inhibitor 98.1% Unkown
HY-147112 MNP-GAL / Unkown
HY-173246 GalNAc-NAG25 phosphoramidite / Unkown
HY-173247 GalNAc-NAG37 phosphoramidite / Unkown
HY-173248 GalNAc-NAG15 phosphoramidite / Unkown
HY-E70184 α-N-Acetylglucosaminidase / Unkown
HY-RS09013 NAGS Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19356 Nags Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25847 Nags Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nags NCBI NCBI:162417