2. Gene
  3. Fnip1 - folliculin interacting protein 1 Gene

Fnip1 - folliculin interacting protein 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as A730024A03Rik

Gene ID: 216742 | Gene type: protein coding

About Fnip1

Summary

Predicted to enable several functions, including ATPase inhibitor activity; chaperone binding activity; and guanyl-nucleotide exchange factor activity. Acts upstream of or within with a positive effect on negative regulation of cell population proliferation. Acts upstream of or within several processes, including immature B cell differentiation; negative regulation of TOR signaling; and regulation of apoptotic process. Located in cytoplasm. Orthologous to human FNIP1 (folliculin interacting protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Fnip1 Products(1)

mRNA Protein Name
NM_173753.4 NP_776114.2 folliculin-interacting protein 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
23582324 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of B cell apoptotic process IMP
IMP: Inferred from mutant phenotype
22608497 MGI
acts upstream of TOR signaling IMP
IMP: Inferred from mutant phenotype
22608497 MGI
acts upstream of or within cellular response to starvation IMP
IMP: Inferred from mutant phenotype
22608497 MGI
acts upstream of or within immature B cell differentiation IMP
IMP: Inferred from mutant phenotype
22608497 MGI
acts upstream of or within negative regulation of TOR signaling IMP
IMP: Inferred from mutant phenotype
22608497 MGI
acts upstream of or within positive effect negative regulation of cell population proliferation IGI
IGI: Inferred from genetic interaction
25775561 MGI
acts upstream of or within negative regulation of cysteine-type endopeptidase activity involved in apoptotic process IGI
IGI: Inferred from genetic interaction
22709692 MGI
acts upstream of or within negative regulation of cysteine-type endopeptidase activity involved in apoptotic process IMP
IMP: Inferred from mutant phenotype
22709692 MGI
acts upstream of or within positive regulation of B cell apoptotic process IGI
IGI: Inferred from genetic interaction
22608497 MGI
acts upstream of or within positive regulation of B cell apoptotic process IMP
IMP: Inferred from mutant phenotype
22608497 MGI
acts upstream of or within regulation of pro-B cell differentiation IMP
IMP: Inferred from mutant phenotype
22709692 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
22608497 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

folliculin-interacting protein 1

Fnip1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
Fnip1 Q68FD7 Flcn Mus musculus Q8QZS3
Anti Tag CoIP
23582324
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-W229874 EN106 99.92% Unkown
HY-RS05023 FNIP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19195 Fnip1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25683 Fnip1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fnip1 NCBI NCBI:96459