2. Gene
  3. Tacc3 - transforming, acidic coiled-coil containing protein 3 Gene

Tacc3 - transforming, acidic coiled-coil containing protein 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Aint; Eric1

Gene ID: 21335 | Gene type: protein coding

About Tacc3

Summary

Enables protein domain specific binding activity. Acts upstream of or within several processes, including astral microtubule organization; cytoplasmic sequestering of transcription factor; and nervous system development. Located in centrosome and cytoplasm. Is expressed in several structures, including alimentary system; brain; early embryo; genitourinary system; and sensory organ. Orthologous to human TACC3 (transforming acidic coiled-coil containing protein 3). [provided by Alliance of Genome Resources, Apr 2022]

Tacc3 Products(12)

mRNA Protein Name
NM_001040435.4 NP_001035525.1 transforming acidic coiled-coil-containing protein 3 isoform 2
NM_001310541.2 NP_001297470.1 transforming acidic coiled-coil-containing protein 3 isoform 1
NM_001405350.1 NP_001392279.1 transforming acidic coiled-coil-containing protein 3 isoform 3
NM_001405351.1 NP_001392280.1 transforming acidic coiled-coil-containing protein 3 isoform 4
NM_001405352.1 NP_001392281.1 transforming acidic coiled-coil-containing protein 3 isoform 5
NM_001405353.1 NP_001392282.1 transforming acidic coiled-coil-containing protein 3 isoform 6
NM_001405354.1 NP_001392283.1 transforming acidic coiled-coil-containing protein 3 isoform 7
NM_001405355.1 NP_001392284.1 transforming acidic coiled-coil-containing protein 3 isoform 8
NM_001405356.1 NP_001392285.1 transforming acidic coiled-coil-containing protein 3 isoform 2
NM_001405357.1 NP_001392286.1 transforming acidic coiled-coil-containing protein 3 isoform 2
NM_001405358.1 NP_001392287.1 transforming acidic coiled-coil-containing protein 3 isoform 9
NM_001405360.1 NP_001392289.1 transforming acidic coiled-coil-containing protein 3 isoform 9
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
15234987 MGI
enables protein domain specific binding IPI
IPI: Inferred from physical interaction
17920017 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within astral microtubule organization IDA
IDA: Inferred from direct assay
17920017 MGI
acts upstream of or within cell population proliferation IMP
IMP: Inferred from mutant phenotype
17920017 MGI
acts upstream of or within cerebral cortex development IMP
IMP: Inferred from mutant phenotype
17920017 MGI
acts upstream of or within cytoplasmic sequestering of transcription factor IDA
IDA: Inferred from direct assay
11025203 MGI
acts upstream of or within hemopoiesis IMP
IMP: Inferred from mutant phenotype
11847113 MGI
acts upstream of or within interkinetic nuclear migration IMP
IMP: Inferred from mutant phenotype
17920017 MGI
acts upstream of or within microtubule cytoskeleton organization IMP
IMP: Inferred from mutant phenotype
17920017 MGI
acts upstream of or within neurogenesis IMP
IMP: Inferred from mutant phenotype
17920017 MGI
acts upstream of or within regulation of cell cycle IGI
IGI: Inferred from genetic interaction
11847113 MGI
acts upstream of or within regulation of microtubule-based process IMP
IMP: Inferred from mutant phenotype
17920017 MGI
acts upstream of or within response to hypoxia IDA
IDA: Inferred from direct assay
11025203 MGI
Cellular Component GO Annotation Evidence Reference Source
located in centrosome IDA
IDA: Inferred from direct assay
11847113 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
11025203 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
11980711 MGI
is active in glutamatergic synapse IEP
IEP: Inferred from expression pattern
11980711 MGI
is active in postsynaptic density IDA
IDA: Inferred from direct assay
11980711 MGI
is active in postsynaptic density IEP
IEP: Inferred from expression pattern
11980711 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transforming acidic coiled-coil-containing protein 3

ARNT-interacting protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (16)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-10996A KHS101 hydrochloride 99.65% Unkown
HY-135960 BO-264 99.76% Unkown
HY-120087 KG-548 Inhibitor 99.92% Unkown
HY-145895 SNIPER(TACC3)-11 Inhibitor 99.58% Unkown
HY-111876 SNIPER(TACC3)-1 99.51% Unkown
HY-111877 SNIPER(TACC3)-2 99.81% Unkown
HY-W012248 KG-655 99.87% Unkown
HY-10996 KHS101 / Unkown
HY-111876A SNIPER(TACC3)-1 hydrochloride / Unkown
HY-111877A SNIPER(TACC3)-2 hydrochloride / Unkown
HY-151985 TACC3 inhibitor 1 Inducer / Unkown
HY-170960 TACC3 inhibitor 2 / Unkown
HY-174981 LC-MF-4 / Unkown
HY-RS14141 TACC3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16930 Tacc3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23373 Tacc3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tacc3 NCBI NCBI:10460