2. Gene
  3. Srpk2 - serine/arginine-rich protein specific kinase 2 Gene

Srpk2 - serine/arginine-rich protein specific kinase 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Wbp6; mSRPK2

Gene ID: 20817 | Gene type: protein coding

About Srpk2

Summary

Enables several functions, including 14-3-3 protein binding activity; ATP binding activity; and magnesium ion binding activity. Involved in several processes, including nuclear speck organization; positive regulation of neuron apoptotic process; and spliceosomal complex assembly. Located in cytoplasm and nucleus. Is expressed in central nervous system; neural retina; and olfactory epithelium. Orthologous to human SRPK2 (SRSF protein kinase 2). [provided by Alliance of Genome Resources, Apr 2022]

Srpk2 Products(32)

mRNA Protein Name
NM_001359172.2 NP_001346101.1 SRSF protein kinase 2 isoform a
NM_001359173.2 NP_001346102.1 SRSF protein kinase 2 isoform b
NM_001359174.2 NP_001346103.1 SRSF protein kinase 2 isoform c
NM_001359175.2 NP_001346104.1 SRSF protein kinase 2 isoform d
NM_001407496.1 NP_001394425.1 SRSF protein kinase 2 isoform f
NM_001407498.1 NP_001394427.1 SRSF protein kinase 2 isoform g
NM_001407499.1 NP_001394428.1 SRSF protein kinase 2 isoform h
NM_001407500.1 NP_001394429.1 SRSF protein kinase 2 isoform i
NM_001407501.1 NP_001394430.1 SRSF protein kinase 2 isoform j
NM_001407502.1 NP_001394431.1 SRSF protein kinase 2 isoform k
NM_001407503.1 NP_001394432.1 SRSF protein kinase 2 isoform l
NM_001407504.1 NP_001394433.1 SRSF protein kinase 2 isoform m
NM_001407505.1 NP_001394434.1 SRSF protein kinase 2 isoform c
NM_001407506.1 NP_001394435.1 SRSF protein kinase 2 isoform n
NM_001407507.1 NP_001394436.1 SRSF protein kinase 2 isoform d
NM_001407508.1 NP_001394437.1 SRSF protein kinase 2 isoform d
NM_001407509.1 NP_001394438.1 SRSF protein kinase 2 isoform d
NM_001407510.1 NP_001394439.1 SRSF protein kinase 2 isoform o
NM_001407511.1 NP_001394440.1 SRSF protein kinase 2 isoform p
NM_001407512.1 NP_001394441.1 SRSF protein kinase 2 isoform p
NM_001407513.1 NP_001394442.1 SRSF protein kinase 2 isoform q
NM_001407514.1 NP_001394443.1 SRSF protein kinase 2 isoform r
NM_001407515.1 NP_001394444.1 SRSF protein kinase 2 isoform s
NM_001407516.1 NP_001394445.1 SRSF protein kinase 2 isoform t
NM_001407517.1 NP_001394446.1 SRSF protein kinase 2 isoform u
NM_001407518.1 NP_001394447.1 SRSF protein kinase 2 isoform v
NM_001407519.1 NP_001394448.1 SRSF protein kinase 2 isoform w
NM_001407520.1 NP_001394449.1 SRSF protein kinase 2 isoform w
NM_001407521.1 NP_001394450.1 SRSF protein kinase 2 isoform x
NM_001407522.1 NP_001394451.1 SRSF protein kinase 2 isoform x
NM_001407523.1 NP_001394452.1 SRSF protein kinase 2 isoform y
NM_009274.3 NP_033300.2 SRSF protein kinase 2 isoform c
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables 14-3-3 protein binding IDA
IDA: Inferred from direct assay
19592491 MGI
enables ATP binding IDA
IDA: Inferred from direct assay
9446799 MGI
enables magnesium ion binding IDA
IDA: Inferred from direct assay
9446799 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
10196197 MGI
enables protein serine/threonine kinase activity IDA
IDA: Inferred from direct assay
9446799 MGI
Biological Process GO Annotation Evidence Reference Source
involved in RNA splicing IDA
IDA: Inferred from direct assay
9446799 MGI
involved in angiogenesis IDA
IDA: Inferred from direct assay
19906640 MGI
involved in intracellular signal transduction IDA
IDA: Inferred from direct assay
9446799 MGI
involved in nuclear speck organization IDA
IDA: Inferred from direct assay
9446799 MGI
involved in positive regulation of cell cycle IDA
IDA: Inferred from direct assay
19592491 MGI
involved in positive regulation of cell population proliferation IDA
IDA: Inferred from direct assay
19592491 MGI
involved in positive regulation of gene expression IDA
IDA: Inferred from direct assay
19592491 MGI
involved in positive regulation of neuron apoptotic process IDA
IDA: Inferred from direct assay
19592491 MGI
involved in protein phosphorylation IDA
IDA: Inferred from direct assay
9446799 MGI
involved in spliceosomal complex assembly IDA
IDA: Inferred from direct assay
9446799 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
9446799 MGI
located in nucleus IDA
IDA: Inferred from direct assay
9446799 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

SRSF protein kinase 2

SFRS protein kinase 2

SR-protein-specific kinase 2

WW domain binding protein 6

serine/threonine-protein kinase SRPK2

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-148518 MSC-1186 Inhibitor 98.95% Unkown
HY-113831 CLK1/2-IN-3 Inhibitor / Unkown
HY-RS13778 SRPK2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18547 Srpk2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25029 Srpk2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Srpk2 NCBI NCBI:6733