2. Gene
  3. Sst - somatostatin Gene

Sst - somatostatin Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as SS; SOM; SRIF; Smst

Gene ID: 20604 | Gene type: protein coding

About Sst

Summary

Predicted to enable identical protein binding activity. Acts upstream of or within regulation of cell migration. Located in extracellular space. Is expressed in several structures, including genitourinary system; gut; limb; nervous system; and sensory organ. Orthologous to human SST (somatostatin). [provided by Alliance of Genome Resources, Apr 2022]

Sst Products(1)

mRNA Protein Name
NM_009215.1 NP_033241.1 somatostatin precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables receptor ligand activity IMP
IMP: Inferred from mutant phenotype
11780120 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within regulation of cell migration IDA
IDA: Inferred from direct assay
11780120 MGI
involved in regulation of postsynaptic membrane neurotransmitter receptor levels EXP
EXP: Inferred from Experiment
32049026 MGI
involved in regulation of postsynaptic membrane neurotransmitter receptor levels IDA
IDA: Inferred from direct assay
32049026 MGI
involved in regulation of postsynaptic membrane neurotransmitter receptor levels IMP
IMP: Inferred from mutant phenotype
32049026 MGI
involved in somatostatin signaling pathway IMP
IMP: Inferred from mutant phenotype
11780120 MGI
Cellular Component GO Annotation Evidence Reference Source
is active in GABA-ergic synapse EXP
EXP: Inferred from Experiment
32049026 MGI
is active in GABA-ergic synapse IDA
IDA: Inferred from direct assay
32049026 MGI
is active in GABA-ergic synapse IMP
IMP: Inferred from mutant phenotype
32049026 MGI
is active in cytosol IDA
IDA: Inferred from direct assay
29960053 MGI
located in extracellular space IDA
IDA: Inferred from direct assay
17928203 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

somatostatin

preprosomatostatin

Related Agents

Approval
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-16381A Pasireotide acetate Agonist 99.25% Unkown
HY-16381 Pasireotide Agonist 99.94% Yes
HY-79135 Pasireotide ditrifluoroacetate Agonist 99.56% Yes
HY-79136 Pasireotide L-aspartate salt Agonist ≥98.0% Unkown
HY-108768 Pasireotide pamoate Agonist 99.47% Yes
HY-16381B Pasireotide (diaspartate) Agonist / Unkown
Clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-P1384 L803 Agonist / Phase 2
HY-P3294 Onzigolide Agonist / Phase 2
Pre-clinical Phase
Bioactive Molecules (34)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P1932 Cortistatin-14 99.84% Unkown
HY-111615A J-2156 TFA Agonist 99.59% Unkown
HY-P1202 CYN 154806 Antagonist 99.97% Unkown
HY-P1202A CYN 154806 TFA Antagonist 99.81% Unkown
HY-P1932A Cortistatin-14 TFA 99.94% Unkown
HY-P1206 CH 275 Agonist 99.71% Unkown
HY-155193 XY-52 Inhibitor 99.77% Unkown
HY-P1201 Cyclosomatostatin Antagonist 99.76% Unkown
HY-P1203 BIM-23056 Antagonist 99.98% Unkown
HY-108497 L-803087 Agonist 99.66% Unkown
HY-P2090A Angiopeptin TFA 99.01% Unkown
HY-123335A L-796778 acetate Agonist 98.00% Unkown
HY-123499 SRA880 Antagonist 98.22% Unkown
HY-108499 NNC 26-9100 99.3% Unkown
HY-P10758 Alkyne-βAG-TOCA Agonist 98.99% Unkown
HY-111615 J-2156 Agonist / Unkown
HY-P10741 DOTA-EB-TATE Activator 95.42% Unkown
HY-P1139 Cortistatin-8 Antagonist 98.86% Unkown
HY-P4469 PRL 3195 / Unkown
HY-108497A L-803087 TFA Agonist / Unkown
HY-108501 (1R,1'S,3'R/1R,1'R,3'S)-L-054,264 Agonist / Unkown
HY-110161 sst2 Receptor agonist-1 Agonist / Unkown
HY-164399 SST0116CL1 / Unkown
HY-177278 SST1 receptor antagonist-1 Antagonist / Unkown
HY-P1201A Cyclosomatostatin TFA Antagonist / Unkown
HY-P1203A BIM-23056 TFA Antagonist / Unkown
HY-P2090 Angiopeptin / Unkown
HY-P3958 BIM-23027 Agonist 99.76% Unkown
HY-RS13819 SST Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-123460 BN-81674 Antagonist / Unkown
HY-164040 Zavolosotine Agonist / Unkown
HY-177282 SST1 receptor antagonist-2 Antagonist / Unkown
HY-RS18024 Sst Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24497 Sst Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sst NCBI NCBI:6750