2. Gene
  3. Rbm4 - RNA binding motif protein 4 Gene

Rbm4 - RNA binding motif protein 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as lark; Lark1; Mlark; Rbm4a; 4921506I22Rik

Gene ID: 19653 | Gene type: protein coding

About Rbm4

Summary

Enables mRNA 3'-UTR binding activity and pre-mRNA binding activity. Involved in circadian regulation of translation; entrainment of circadian clock by photoperiod; and regulation of nucleocytoplasmic transport. Acts upstream of or within several processes, including Insulin secretion involved in cellular response to glucose stimulus; regulation of gene expression; and regulation of Insulin Receptor signaling pathway. Located in nucleolus and perinuclear region of cytoplasm. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human RBM4 (RNA binding motif protein 4). [provided by Alliance of Genome Resources, Apr 2022]

Rbm4 Products(5)

mRNA Protein Name
NM_001290122.1 NP_001277051.1 RNA-binding protein 4 isoform a
NM_001290123.1 NP_001277052.1 RNA-binding protein 4 isoform a
NM_001290124.1 NP_001277053.1 RNA-binding protein 4 isoform b
NM_001290125.1 NP_001277054.1 RNA-binding protein 4 isoform b
NM_009032.3 NP_033058.2 RNA-binding protein 4 isoform a
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables mRNA 3'-UTR binding IDA
IDA: Inferred from direct assay
17264215 MGI
enables pre-mRNA binding IDA
IDA: Inferred from direct assay
16260624 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within circadian regulation of gene expression IMP
IMP: Inferred from mutant phenotype
17264215 MGI
involved in circadian regulation of translation IDA
IDA: Inferred from direct assay
17264215 MGI
acts upstream of or within enteroendocrine cell differentiation IMP
IMP: Inferred from mutant phenotype
23129807 MGI
involved in entrainment of circadian clock by photoperiod IDA
IDA: Inferred from direct assay
17264215 MGI
acts upstream of or within glucose homeostasis IMP
IMP: Inferred from mutant phenotype
23129807 MGI
acts upstream of or within insulin secretion involved in cellular response to glucose stimulus IMP
IMP: Inferred from mutant phenotype
23129807 MGI
acts upstream of or within pancreas development IMP
IMP: Inferred from mutant phenotype
23129807 MGI
acts upstream of or within positive regulation of translation IDA
IDA: Inferred from direct assay
17264215 MGI
acts upstream of or within regulation of alternative mRNA splicing, via spliceosome IMP
IMP: Inferred from mutant phenotype
23129807 MGI
acts upstream of or within regulation of gene expression IMP
IMP: Inferred from mutant phenotype
23129807 MGI
acts upstream of or within regulation of insulin receptor signaling pathway IDA
IDA: Inferred from direct assay
23129807 MGI
involved in regulation of nucleocytoplasmic transport IDA
IDA: Inferred from direct assay
19801630 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
19801630 MGI
located in nucleolus IDA
IDA: Inferred from direct assay
19801630 MGI
located in nucleus IDA
IDA: Inferred from direct assay
19801630 MGI
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
19801630 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

RNA-binding protein 4

RNA-binding motif protein 4a

lark homolog

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11752 RBM4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19942 Rbm4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26444 Rbm4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rbm4 NCBI NCBI:5936