2. Gene
  3. Klk6 - kallikrein related-peptidase 6 Gene

Klk6 - kallikrein related-peptidase 6 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as BSP; MSP; Bssp; Klk29; Prss9; Prss18; neurosin

Gene ID: 19144 | Gene type: protein coding

About Klk6

Summary

Predicted to enable serine-type endopeptidase activity. Predicted to be involved in positive regulation of G protein-coupled receptor signaling pathway and regulation of neuron projection development. Predicted to be located in cytoplasm and extracellular region. Predicted to be active in secretory granule. Is expressed in several structures, including brain. Human ortholog(s) of this gene implicated in Alzheimer's disease; Lewy body dementia; Parkinson's disease; demyelinating disease; and multiple system atrophy. Orthologous to human KLK6 (Kallikrein related peptidase 6). [provided by Alliance of Genome Resources, Apr 2022]

Klk6 Products(4)

mRNA Protein Name
NM_001164696.1 NP_001158168.1 kallikrein-6 precursor
NM_001164697.1 NP_001158169.1 kallikrein-6 precursor
NM_001164698.1 NP_001158170.1 kallikrein-6 precursor
NM_011177.2 NP_035307.2 kallikrein-6 precursor
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
is active in cornified envelope IDA
IDA: Inferred from direct assay
26644517 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

kallikrein-6

brain serine protease

kallikrein 29

kallikrein 6

myelencephalon-specific protease

myofibril-bound protease

protease M

protease, serine, 18

protease, serine, 9

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07384 KLK6 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS17290 Klk6 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS23745 Klk6 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Klk6 NCBI NCBI:5653