2. Gene
  3. Pole - polymerase (DNA directed), epsilon Gene

Pole - polymerase (DNA directed), epsilon Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus
Gene ID: 18973 | Gene type: protein coding

About Pole

Summary

Predicted to enable DNA binding activity; catalytic activity, acting on DNA; and chromatin binding activity. Predicted to be involved in DNA metabolic process and G1/S transition of mitotic cell cycle. Predicted to act upstream of or within DNA repair. Predicted to be located in nucleoplasm and plasma membrane. Predicted to be part of epsilon DNA Polymerase complex. Is expressed in nervous system. Human ortholog(s) of this gene implicated in colorectal Cancer. Orthologous to human POLE (DNA Polymerase epsilon, catalytic subunit). [provided by Alliance of Genome Resources, Apr 2022]

Pole Products(1)

mRNA Protein Name
NM_011132.2 NP_035262.2 DNA polymerase epsilon catalytic subunit A
Protein Preferred Names Protein Names

DNA polymerase epsilon catalytic subunit A

3'-5' exodeoxyribonuclease

DNA polymerase II subunit A

DNA-directed DNA polymerase epsilon

pol-epsilon

Related Agents

Pre-clinical Phase
Bioactive Molecules (10)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-153066 VLS-1272 98.09% Unkown
HY-121908 FCPT Inhibitor / Unkown
HY-RS10825 POLE Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS10826 POLE2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS10827 POLE3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS10828 POLE4 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-B0824A (1R)-cis-Bifenthrin / Unkown
HY-RS17692 Pole Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS22734 Pole2 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24154 Pole Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pole NCBI NCBI:5426