Pitpna - phosphatidylinositol transfer protein, alpha Gene

Mus musculus

Also known as vb; Pitpn; vibrator

Gene ID: 18738 | Gene type: protein coding

About Pitpna

Summary

This gene encodes a member of a family of lipid-binding proteins that transfer molecules of phosphatidylinositol or phosphatidylcholine between membrane surfaces. The protein is implicated in Phospholipase C signaling and in the production of phosphatidylinositol 3,4,5-trisphosphate by phosphoinositide-3-kinase. [provided by RefSeq, Sep 2015]

Pitpna Products(1)

mRNA	Protein	Name
NM_008850.2	NP_032876.1	phosphatidylinositol transfer protein alpha isoform

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables phosphatidylcholine binding	IDA IDA: Inferred from direct assay	8049244	MGI
enables phosphatidylcholine transfer activity	IDA IDA: Inferred from direct assay	8049244	MGI
enables phosphatidylinositol binding	IDA IDA: Inferred from direct assay	8049244	MGI
enables phosphatidylinositol transfer activity	IDA IDA: Inferred from direct assay	8049244	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in axonogenesis	IMP IMP: Inferred from mutant phenotype	16244667	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in cytoplasm	IDA IDA: Inferred from direct assay	7654206	MGI
located in nucleus	IDA IDA: Inferred from direct assay	7654206	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

phosphatidylinositol transfer protein alpha isoform

PI-TP-alpha	Pitp alpha
ptdIns transfer protein alpha	ptdInsTP alpha

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10574	PITPNA Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS21908	Pitpna Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS28425	Pitpna Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Pitpna	NCBI	NCBI:5306

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