2. Gene
  3. Pappa - pregnancy-associated plasma protein A Gene

Pappa - pregnancy-associated plasma protein A Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as PAG1; PAPP-A; IGFBP-4ase; 8430414N03Rik

Gene ID: 18491 | Gene type: protein coding

About Pappa

Summary

Enables endopeptidase activity. Predicted to be involved in proteolysis. Located in extracellular space. Is expressed in several structures, including gut; limb; paraxial mesenchyme; reproductive system; and sensory organ. Human ortholog(s) of this gene implicated in myocardial infarction. Orthologous to human PAPPA (pappalysin 1). [provided by Alliance of Genome Resources, Apr 2022]

Pappa Products(1)

mRNA Protein Name
NM_021362.2 NP_067337.1 pappalysin-1 precursor
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables endopeptidase activity IDA
IDA: Inferred from direct assay
11985604 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

pappalysin-1

IGF-dependent IGFBP-4 protease

insulin-like growth factor-dependent IGF-binding protein 4 protease

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10028 PAPPA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10029 PAPPA2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17709 Pappa Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24174 Pappa Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pappa NCBI NCBI:5069