2. Gene
  3. Mybl2 - myeloblastosis oncogene-like 2 Gene

Mybl2 - myeloblastosis oncogene-like 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Bmyb; B-Myb

Gene ID: 17865 | Gene type: protein coding

About Mybl2

Summary

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within cellular response to Leukemia Inhibitory Factor and mitotic spindle assembly. Located in nucleus. Part of Myb complex. Is expressed in several structures, including brain; early conceptus; genitourinary system; hemolymphoid system; and skin. Used to study acute myeloid leukemia and myelodysplastic syndrome. Orthologous to human MYBL2 (MYB proto-oncogene like 2). [provided by Alliance of Genome Resources, Apr 2022]

Mybl2 Products(1)

mRNA Protein Name
NM_008652.2 NP_032678.1 myb-related protein B
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: Inferred from expression pattern
20439489 MGI
acts upstream of or within mitotic spindle assembly IDA
IDA: Inferred from direct assay
18548008 MGI
Cellular Component GO Annotation Evidence Reference Source
part of Myb complex IDA
IDA: Inferred from direct assay
18548008 MGI
located in nucleus IDA
IDA: Inferred from direct assay
11114719 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

myb-related protein B

myb-like protein 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08872 MYBL2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20059 Mybl2 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26563 Mybl2 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mybl2 NCBI NCBI:4605