Mybl1 - myeloblastosis oncogene-like 1 Gene

Mus musculus

Also known as A-myb; repro9; G1-419-6

Gene ID: 17864 | Gene type: protein coding

About Mybl1

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific. Involved in several processes, including male gamete generation; negative regulation of transposition; and piRNA biosynthetic process. Located in nucleus. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; hemolymphoid system gland; and sensory organ. Orthologous to human MYBL1 (MYB proto-oncogene like 1). [provided by Alliance of Genome Resources, Apr 2022]

Mybl1 Products(2)

mRNA	Protein	Name
NM_001290397.1	NP_001277326.1	myb-related protein A isoform 2
NM_008651.3	NP_032677.2	myb-related protein A isoform 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables DNA-binding transcription activator activity, RNA polymerase II-specific	IDA IDA: Inferred from direct assay	29848638	MGI
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IDA IDA: Inferred from direct assay	23523368	MGI
enables promoter-specific chromatin binding	IDA IDA: Inferred from direct assay	26624618	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in male meiosis I	IMP IMP: Inferred from mutant phenotype	21750041	MGI
involved in positive regulation of piRNA transcription	IDA IDA: Inferred from direct assay	23523368	MGI
involved in positive regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	23523368	MGI
involved in positive regulation of transcription by RNA polymerase II	IMP IMP: Inferred from mutant phenotype	21750041	MGI
involved in spermatogenesis	IMP IMP: Inferred from mutant phenotype	21750041	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in nucleus	IDA IDA: Inferred from direct assay	21750041	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

myb-related protein A

myb-like protein 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08871	MYBL1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS21658	Mybl1 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Mybl1	NCBI	NCBI:4603

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