Eef1a1 - eukaryotic translation elongation factor 1 alpha 1 Gene

Rattus norvegicus

Also known as SI; EF1A; EEF-1; EEF1A; Eef1a2; Eef1a2l1

Gene ID: 171361 | Gene type: protein coding

About Eef1a1

Summary

Enables identical protein binding activity and mRNA binding activity. Involved in several processes, including cellular response to nerve growth factor stimulus; negative regulation of Reactive Oxygen Species biosynthetic process; and positive regulation of neuron projection development. Located in cytosol and nucleus. Orthologous to human EEF1A1 (eukaryotic translation elongation factor 1 alpha 1). [provided by Alliance of Genome Resources, Apr 2022]

Eef1a1 Products(1)

mRNA	Protein	Name
NM_175838.2	NP_787032.1	elongation factor 1-alpha 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables heterocyclic compound binding	IPI IPI: Inferred from physical interaction	18218611	RGD
enables identical protein binding	IPI IPI: Inferred from physical interaction	19501573	RGD
enables mRNA binding	IDA IDA: Inferred from direct assay	19501573	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in cellular response to nerve growth factor stimulus	IEP IEP: Inferred from expression pattern	11907030	RGD
involved in cellular response to xenobiotic stimulus	IEP IEP: Inferred from expression pattern	21390260	RGD
involved in negative regulation of reactive oxygen species biosynthetic process	IMP IMP: Inferred from mutant phenotype	23041468	RGD
involved in positive regulation of apoptotic process	IMP IMP: Inferred from mutant phenotype	16319173	RGD
involved in positive regulation of neuron projection development	IMP IMP: Inferred from mutant phenotype	21390260	RGD
involved in regulation of postsynaptic specialization assembly	IDA IDA: Inferred from direct assay	23839781	RGD
involved in regulation of postsynaptic specialization assembly	IMP IMP: Inferred from mutant phenotype	23839781	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
is active in GABA-ergic synapse	IDA IDA: Inferred from direct assay	23839781	RGD
is active in GABA-ergic synapse	IMP IMP: Inferred from mutant phenotype	23839781	RGD
is active in postsynapse	IDA IDA: Inferred from direct assay	15265584	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

elongation factor 1-alpha 1

EF-1 alpha2	EF-1-alpha-1
EF-Tu	eEF1A-1
elongation factor 1 A-1	elongation factor Tu
eukaryotic elongation factor 1 A-1	eukaryotic translation elongation factor 1 alpha 2 like 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (6)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04174	EEF1A1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-123035	Gamendazole	Inhibitor	99.44%	Unkown
HY-P3818	PKCδ Peptide Substrate		/	Unkown
HY-RS04178	EEF1E1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS18307	Eef1a1 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS24785	Eef1a1 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Eef1a1	NCBI	NCBI:1915

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