2. Gene
  3. Madcam1 - mucosal vascular addressin cell adhesion molecule 1 Gene

Madcam1 - mucosal vascular addressin cell adhesion molecule 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as MAdCAM-1

Gene ID: 17123 | Gene type: protein coding

About Madcam1

Summary

Predicted to enable Integrin binding activity involved in cell-matrix adhesion. Acts upstream of or within keratinocyte differentiation and leukocyte migration. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in eyelid; hair follicle; and hemolymphoid system. Orthologous to human MADCAM1 (mucosal vascular addressin cell adhesion molecule 1). [provided by Alliance of Genome Resources, Apr 2022]

Madcam1 Products(2)

mRNA Protein Name
NM_001358785.1 NP_001345714.1 mucosal addressin cell adhesion molecule 1 isoform 2 precursor
NM_013591.3 NP_038619.2 mucosal addressin cell adhesion molecule 1 isoform 1 precursor
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within keratinocyte differentiation IMP
IMP: Inferred from mutant phenotype
12230506 MGI
acts upstream of or within leukocyte migration IMP
IMP: Inferred from mutant phenotype
15484189 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mucosal addressin cell adhesion molecule 1

cell adhesion molecule 1

Recombinant Madcam1 Proteins

Cat. No. Product Name Accession Purity
HY-P77748 MAdCAM1 Protein, Mouse (HEK293, His) Q61826-1 (Q22-S364) ≥95%

Related Agents

Clinical Phase
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99411 Ontamalimab 99.68% Phase 3
Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-159179 α4 integrin receptor antagonist 3 Inhibitor / Unkown
HY-RS07952 MADCAM1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19091 Madcam1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25581 Madcam1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P990203 Anti-Mouse LPAM-1/Integrin α4β7 Antibody (DATK32) Inhibitor 95.00% Unkown
HY-P990197 Anti-Mouse MAdCAM-1 Antibody (MECA-367) Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Madcam1 NCBI NCBI:8174
Macaca fascicularis Madcam1 NCBI NCBI:102125701