2. Gene
  3. Cblb - Cbl proto-oncogene B Gene

Cblb - Cbl proto-oncogene B Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 171136 | Gene type: protein coding

About Cblb

Summary

Enables protein kinase binding activity. Involved in response to gravity; response to hormone; and signal transduction. Located in membrane raft. Used to study type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma and type 1 diabetes mellitus. Orthologous to human CBLB (Cbl proto-oncogene B). [provided by Alliance of Genome Resources, Apr 2022]

Cblb Products(1)

mRNA Protein Name
NM_133601.1 NP_598285.1 E3 ubiquitin-protein ligase CBL-B
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein kinase binding IPI
IPI: Inferred from physical interaction
14531861 RGD
Biological Process GO Annotation Evidence Reference Source
involved in cellular response to hydrogen peroxide IEP
IEP: Inferred from expression pattern
14715702 RGD
involved in negative regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
19546888 RGD
involved in response to gravity IEP
IEP: Inferred from expression pattern
14715702 RGD
involved in response to hormone IEP
IEP: Inferred from expression pattern
16984225 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase CBL-B

Cas-Br-M (murine) ecotropic retroviral transforming sequence b

Cas-Br-M (murine) ectropic retroviral transforming sequence b

Casitas B-lineage lymphoma b

Cbl proto-oncogene B, E3 ubiquitin protein ligase

Cbl proto-oncogene, E3 ubiquitin protein ligase

Related Agents

Pre-clinical Phase
Bioactive Molecules (24)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-141432 NX-1607 Inhibitor 99.87% Unkown
HY-136339 Cbl-b-IN-1 Inhibitor 99.66% Unkown
HY-141431 Cbl-b-IN-2 Inhibitor / Unkown
HY-155120 Cbl-b-IN-5 Inhibitor 99.61% Unkown
HY-156768 Cbl-b-IN-12 Inhibitor / Unkown
HY-155477 Cbl-b-IN-15 Inhibitor / Unkown
HY-156762 Cbl-b-IN-6 Inhibitor / Unkown
HY-156763 Cbl-b-IN-7 Inhibitor / Unkown
HY-156764 Cbl-b-IN-8 Inhibitor / Unkown
HY-156765 Cbl-b-IN-9 Inhibitor / Unkown
HY-156766 Cbl-b-IN-10 Inhibitor / Unkown
HY-156767 Cbl-b-IN-11 Inhibitor / Unkown
HY-156769 Cbl-b-IN-13 Inhibitor / Unkown
HY-158171 Cbl-b-IN-17 Inhibitor / Unkown
HY-158173 Cbl-b-IN-19 Inhibitor / Unkown
HY-159608 PROTAC Cbl-b-IN-1 / Unkown
HY-161977 Cbl-b-IN-26 Inhibitor / Unkown
HY-163194 Cbl-b-IN-16 Inhibitor / Unkown
HY-169005 Cbl-b-IN-27 Inhibitor / Unkown
HY-173311 Cbl-b-IN-28 / Unkown
HY-RS01997 CBLB Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-141432G NX-1607 (GMP) Inhibitor / Unkown
HY-RS17948 Cblb Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24419 Cblb Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P991076 Entolimod Agonist / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cblb NCBI NCBI:868