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  3. Kcnj2 - potassium inwardly-rectifying channel, subfamily J, member 2 Gene

Kcnj2 - potassium inwardly-rectifying channel, subfamily J, member 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as IRK1; Kcnf1; Kir2.1

Gene ID: 16518 | Gene type: protein coding

About Kcnj2

Summary

Enables identical protein binding activity. Acts upstream of or within cardiac muscle cell action potential and magnesium ion transport. Predicted to be located in several cellular components, including T-tubule; endoplasmic reticulum; and intercalated disc. Predicted to be intrinsic component of membrane. Predicted to be part of voltage-gated Potassium Channel complex. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; heart; and sensory organ. Human ortholog(s) of this gene implicated in Andersen-Tawil syndrome; familial atrial fibrillation; familial periodic paralysis; and short QT syndrome. Orthologous to human KCNJ2 (potassium inwardly rectifying channel subfamily J member 2). [provided by Alliance of Genome Resources, Apr 2022]

Kcnj2 Products(2)

mRNA Protein Name
NM_008425.4 NP_032451.1 inward rectifier potassium channel 2
NM_008425.4 NP_032451.1 inward rectifier potassium channel 2
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
16834334 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
11287423 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within cardiac muscle cell action potential IMP
IMP: Inferred from mutant phenotype
15581370 MGI
acts upstream of or within magnesium ion transport IDA
IDA: Inferred from direct assay
8189383 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

inward rectifier potassium channel 2

IRK-1

inward rectifier K(+) channel Kir2.1

potassium channel, inwardly rectifying subfamily J member 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07145 KCNJ2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20045 Kcnj2 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26548 Kcnj2 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kcnj2 NCBI NCBI:3759