2. Gene
  3. Lef1 - lymphoid enhancer binding factor 1 Gene

Lef1 - lymphoid enhancer binding factor 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 161452 | Gene type: protein coding

About Lef1

Summary

Predicted to enable several functions, including DNA binding activity; DNA-binding transcription factor activity, RNA polymerase II-specific; and protein domain specific binding activity. Involved in several processes, including animal organ development; odontoblast differentiation; and response to lithium ion. Located in nucleus. Human ortholog(s) of this gene implicated in ovarian Cancer. Orthologous to human LEF1 (lymphoid enhancer binding factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Lef1 Products(1)

mRNA Protein Name
NM_130429.2 NP_569113.2 lymphoid enhancer-binding factor 1
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
17170212 RGD
Biological Process GO Annotation Evidence Reference Source
involved in animal organ regeneration IEP
IEP: Inferred from expression pattern
18990226 RGD
involved in cell adhesion IEP
IEP: Inferred from expression pattern
9539744 RGD
involved in kidney development IEP
IEP: Inferred from expression pattern
17329570 RGD
involved in odontoblast differentiation IMP
IMP: Inferred from mutant phenotype
20425127 RGD
involved in response to organic cyclic compound IEP
IEP: Inferred from expression pattern
17329570 RGD
involved in skin development IEP
IEP: Inferred from expression pattern
17244330 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

lymphoid enhancer-binding factor 1

LEF-1

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07584 LEF1 Human Pre-designed siRNA Set A Pre-designed Sets ≥90.0% Unkown
HY-RS18620 Lef1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25106 Lef1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lef1 NCBI NCBI:51176