1. Gene
  2. Fkbp5 - FK506 binding protein 5 Gene

Fkbp5 - FK506 binding protein 5 Gene

Mus musculus

Also known as Dit1; FKBP-5; FKBP51; D17Ertd592e

Gene ID: 14229 | Gene type: protein coding

About Fkbp5

Summary

Predicted to enable heat shock protein binding activity and peptidyl-prolyl cis-trans isomerase activity. Acts upstream of or within response to bacterium. Predicted to be located in nucleoplasm. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; brain; hemolymphoid system gland; integumental system; and reproductive system. Human ortholog(s) of this gene implicated in major depressive disorder. Orthologous to human FKBP5 (FKBP prolyl isomerase 5). [provided by Alliance of Genome Resources, Apr 2022]

Fkbp5 Products(1)

mRNA Protein Name
NM_010220.4 NP_034350.1 peptidyl-prolyl cis-trans isomerase FKBP5
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
11751894 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within response to bacterium IEP
IEP: Inferred from expression pattern
23012479 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

peptidyl-prolyl cis-trans isomerase FKBP5

51 kDa FK506-binding protein

51 kDa FKBP

PPIase FKBP5

rotamase

Fkbp5 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
Fkbp5 Q64378 Nr3c1 Mus musculus P06537 11751894
Cross: Cross-species interaction Intra: Intraspecies interaction

Orthologs Information

Species Symbol Source ID
Homo sapiens Fkbp5 NCBI NCBI:2289