2. Gene
  3. Eya2 - EYA transcriptional coactivator and phosphatase 2 Gene

Eya2 - EYA transcriptional coactivator and phosphatase 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Eab1

Gene ID: 14049 | Gene type: protein coding

About Eya2

Summary

This gene encodes a member of the eyes absent protein family. The encoded protein is a tyrosine Phosphatase which acts as a transcriptional activator during development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]

Eya2 Products(3)

mRNA Protein Name
NM_001271962.2 NP_001258891.1 eyes absent homolog 2
NM_001271963.2 NP_001258892.1 eyes absent homolog 2
NM_010165.4 NP_034295.1 eyes absent homolog 2
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
20956555 MGI
enables protein tyrosine phosphatase activity IDA
IDA: Inferred from direct assay
14628052 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within extrinsic apoptotic signaling pathway in absence of ligand IDA
IDA: Inferred from direct assay
11700312 MGI
acts upstream of or within mitochondrial outer membrane permeabilization IDA
IDA: Inferred from direct assay
11700312 MGI
acts upstream of or within protein dephosphorylation IDA
IDA: Inferred from direct assay
14628052 MGI
acts upstream of or within striated muscle tissue development IGI
IGI: Inferred from genetic interaction
17098221 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
11700312 MGI
NOT located in nucleolus IDA
IDA: Inferred from direct assay
11700312 MGI
located in nucleus IDA
IDA: Inferred from direct assay
11700312 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

eyes absent homolog 2

eyes absent 2 homolog

Related Agents

Pre-clinical Phase
Bioactive Molecules (7)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-138657 NCGC00378430 Inhibitor 99.58% Unkown
HY-133512 NCGC00249987 Inhibitor 99.91% Unkown
HY-133511 MLS000544460 Inhibitor 99.42% Unkown
HY-162592 EYA2-IN-1 / Unkown
HY-RS04612 EYA2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS19599 Eya2 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26095 Eya2 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Eya2 NCBI NCBI:2139