2. Gene
  3. Evl - Ena-vasodilator stimulated phosphoprotein Gene

Evl - Ena-vasodilator stimulated phosphoprotein Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as b2b2600Clo

Gene ID: 14026 | Gene type: protein coding

About Evl

Summary

Enables SH3 domain binding activity and profilin binding activity. Involved in actin polymerization or depolymerization and positive regulation of actin filament polymerization. Acts upstream of or within cellular response to interferon-gamma. Located in focal adhesion; lamellipodium; and phagocytic vesicle. Is expressed in several structures, including central nervous system; genitourinary system; immune system; retina; and small intestine. Orthologous to human EVL (Enah/Vasp-like). [provided by Alliance of Genome Resources, Apr 2022]

Evl Products(4)

mRNA Protein Name
NM_001163394.1 NP_001156866.1 ena/VASP-like protein isoform 1
NM_001163395.1 NP_001156867.1 ena/VASP-like protein isoform 3
NM_001163396.2 NP_001156868.1 ena/VASP-like protein isoform 4
NM_007965.3 NP_031991.3 ena/VASP-like protein isoform 2
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables SH3 domain binding IDA
IDA: Inferred from direct assay
10945997 MGI
enables profilin binding IDA
IDA: Inferred from direct assay
10945997 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
10993894 MGI
Biological Process GO Annotation Evidence Reference Source
involved in actin polymerization or depolymerization IDA
IDA: Inferred from direct assay
10945997 MGI
acts upstream of or within cellular response to type II interferon IDA
IDA: Inferred from direct assay
19144319 MGI
involved in positive regulation of actin filament polymerization IDA
IDA: Inferred from direct assay
23153535 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
10945997 MGI
located in focal adhesion IDA
IDA: Inferred from direct assay
10945997 MGI
located in lamellipodium IDA
IDA: Inferred from direct assay
10945997 MGI
located in phagocytic vesicle IDA
IDA: Inferred from direct assay
19144319 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ena/VASP-like protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04577 EVL Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS21283 Evl Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Evl NCBI NCBI:51466