Stom - stomatin Gene

Mus musculus

Also known as Epb7.2

Gene ID: 13830 | Gene type: protein coding

About Stom

Summary

Enables protein homodimerization activity. Involved in several processes, including positive regulation by host of viral genome replication; positive regulation of protein targeting to membrane; and regulation of acid-sensing ion channel activity. Located in mitochondrion and perinuclear region of cytoplasm. Is integral component of plasma membrane. Is expressed in bladder; gut; and liver lobe. Orthologous to human STOM (stomatin). [provided by Alliance of Genome Resources, Apr 2022]

Stom Products(1)

mRNA	Protein	Name
NM_013515.2	NP_038543.1	stomatin

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables identical protein binding	IPI IPI: Inferred from physical interaction	22850675	MGI
enables ion channel inhibitor activity	IDA IDA: Inferred from direct assay	22850675	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	22850675	MGI
enables protein homodimerization activity	IPI IPI: Inferred from physical interaction	22850675	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in positive regulation by host of viral genome replication	IMP IMP: Inferred from mutant phenotype	25262680	MGI
involved in positive regulation of protein targeting to membrane	IMP IMP: Inferred from mutant phenotype	25262680	MGI
involved in positive regulation of viral process	IMP IMP: Inferred from mutant phenotype	25262680	MGI
involved in regulation of monoatomic ion transmembrane transport	IDA IDA: Inferred from direct assay	22850675	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in cytoplasm	IDA IDA: Inferred from direct assay	25262680	MGI
located in mitochondrion	IDA IDA: Inferred from direct assay	25262680	MGI
located in perinuclear region of cytoplasm	IDA IDA: Inferred from direct assay	25262680	MGI
located in plasma membrane	IDA IDA: Inferred from direct assay	22850675	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

stomatin

erythrocyte band 7 integral membrane protein	erythrocyte membrane protein band 7.2
erythrocyte protein band 7.2	erythrocyte protein band 7.2
protein 7.2b	protein 7.2b

Related Agents

Approval

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-17015A	Peramivir		99.32%	Unkown

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13949	STOM Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS16927	Stom Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS23370	Stom Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Stom	NCBI	NCBI:2040
Canis familiaris	Stom	NCBI	NCBI:612719
Rattus norvegicus	Stom	NCBI	NCBI:296655
Macaca mulatta	Stom	NCBI	NCBI:699584

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