2. Gene
  3. Dsc2 - desmocollin 2 Gene

Dsc2 - desmocollin 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus
Gene ID: 13506 | Gene type: protein coding

About Dsc2

Summary

This gene encodes a member of the desmocollin protein subfamily. Desmocollins are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

Dsc2 Products(3)

mRNA Protein Name
NM_001317363.1 NP_001304292.1 desmocollin-2 isoform 3
NM_001317365.1 NP_001304294.1 desmocollin-2 isoform Dsc2a preproprotein
NM_013505.4 NP_038533.1 desmocollin-2 isoform Dsc2b preproprotein
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within cellular response to starvation IEP
IEP: Inferred from expression pattern
23260145 MGI
Cellular Component GO Annotation Evidence Reference Source
located in adherens junction IDA
IDA: Inferred from direct assay
15775979 MGI
located in desmosome IDA
IDA: Inferred from direct assay
9864371 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

desmocollin-2

epithelial type 2 desmocollin

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04015 DSC2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04016 DSC3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18351 Dsc2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24830 Dsc2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dsc2 NCBI NCBI:1824
Rattus norvegicus Dsc2 NCBI NCBI:291760