2. Gene
  3. Dctn1 - dynactin 1 Gene

Dctn1 - dynactin 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as p150; Glued; DP-150; DAP-150; p150-glued; p150

Gene ID: 13191 | Gene type: protein coding

About Dctn1

Summary

Enables microtubule binding activity. Acts upstream of or within melanosome transport. Located in cell leading edge and microtubule Cytoskeleton. Part of protein-containing complex. Is expressed in brain; embryo; and head. Human ortholog(s) of this gene implicated in Perry syndrome; amyotrophic lateral sclerosis type 1; and distal hereditary motor neuronopathy type 7B. Orthologous to human DCTN1 (dynactin subunit 1). [provided by Alliance of Genome Resources, Apr 2022]

Dctn1 Products(9)

mRNA Protein Name
NM_001198866.2 NP_001185795.1 dynactin subunit 1 isoform 2
NM_001198867.2 NP_001185796.1 dynactin subunit 1 isoform 3
NM_001347310.2 NP_001334239.1 dynactin subunit 1 isoform 4
NM_001409578.1 NP_001396507.1 dynactin subunit 1 isoform 5
NM_001409579.1 NP_001396508.1 dynactin subunit 1 isoform 6
NM_001409580.1 NP_001396509.1 dynactin subunit 1 isoform 7
NM_001409581.1 NP_001396510.1 dynactin subunit 1 isoform 8
NM_001409582.1 NP_001396511.1 dynactin subunit 1 isoform 3
NM_007835.3 NP_031861.2 dynactin subunit 1 isoform 1
Protein Preferred Names Protein Names

dynactin subunit 1

150 kDa dynein-associated polypeptide

dynactin 1, retrograde axonal transport

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03593 DCTN1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19427 Dctn1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25918 Dctn1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dctn1 NCBI NCBI:1639