2. Gene
  3. Chkb - choline kinase beta Gene

Chkb - choline kinase beta Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Ck; Ek; Ckb; Chkl; Chetk; Ck/Ek; Ckekb; Ck/Ek-beta

Gene ID: 12651 | Gene type: protein coding

About Chkb

Summary

Enables Choline Kinase activity. Acts upstream of or within muscle organ development and phosphatidylcholine biosynthetic process. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; central nervous system; cranium; heart; and sensory organ. Used to study megaconial type congenital muscular dystrophy. Human ortholog(s) of this gene implicated in intellectual disability; megaconial type congenital muscular dystrophy; muscular dystrophy; narcolepsy; and recurrent hypersomnia. Orthologous to human CHKB (Choline Kinase beta). [provided by Alliance of Genome Resources, Apr 2022]

Chkb Products(1)

mRNA Protein Name
NM_007692.6 NP_031718.1 choline/ethanolamine kinase
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables choline kinase activity IMP
IMP: Inferred from mutant phenotype
16371353 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within muscle organ development IMP
IMP: Inferred from mutant phenotype
16371353 MGI
acts upstream of or within phosphatidylcholine biosynthetic process IMP
IMP: Inferred from mutant phenotype
16371353 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

choline/ethanolamine kinase

choline/ethanolamine kinase-b

choline/ethanolaminekinase

ethanolamine kinase

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02634 CHKB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22118 Chkb Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Chkb NCBI NCBI:1120