2. Gene
  3. Cer1 - cerberus 1, DAN family BMP antagonist Gene

Cer1 - cerberus 1, DAN family BMP antagonist Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Cerl; Cerl1; Cerr1; cer-1

Gene ID: 12622 | Gene type: protein coding

About Cer1

Summary

Enables protein homodimerization activity. Involved in negative regulation of mesoderm development; negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; and ureteric bud development. Acts upstream of or within several processes, including cellular response to cadmium ion; growth plate cartilage chondrocyte proliferation; and signal transduction involved in regulation of gene expression. Located in extracellular space. Is expressed in several structures, including alimentary system; brain; genitourinary system; paraxial mesenchyme; and sensory organ. Orthologous to human CER1 (cerberus 1, Dan family BMP antagonist). [provided by Alliance of Genome Resources, Apr 2022]

Cer1 Products(1)

mRNA Protein Name
NM_009887.2 NP_034017.1 cerberus precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein homodimerization activity IDA
IDA: Inferred from direct assay
10748465 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within anterior/posterior axis specification IDA
IDA: Inferred from direct assay
15004567 MGI
acts upstream of or within anterior/posterior axis specification IGI
IGI: Inferred from genetic interaction
15004567 MGI
acts upstream of or within anterior/posterior pattern specification IDA
IDA: Inferred from direct assay
9501024 MGI
acts upstream of or within cell migration involved in gastrulation IGI
IGI: Inferred from genetic interaction
15004567 MGI
acts upstream of cell population proliferation IGI
IGI: Inferred from genetic interaction
15004567 MGI
acts upstream of or within cellular response to cadmium ion IDA
IDA: Inferred from direct assay
15219627 MGI
acts upstream of or within gastrulation IGI
IGI: Inferred from genetic interaction
18241853 MGI
involved in growth plate cartilage chondrocyte proliferation IEP
IEP: Inferred from expression pattern
19113921 MGI
acts upstream of or within negative regulation of BMP signaling pathway IDA
IDA: Inferred from direct assay
9431803 MGI
NOT involved in negative regulation of Wnt signaling pathway IDA
IDA: Inferred from direct assay
10748465 MGI
involved in negative regulation of activin receptor signaling pathway IDA
IDA: Inferred from direct assay
10748465 MGI
acts upstream of or within negative regulation of cell population proliferation IGI
IGI: Inferred from genetic interaction
15004567 MGI
involved in negative regulation of mesoderm development IDA
IDA: Inferred from direct assay
10748465 MGI
involved in sequestering of BMP in extracellular matrix IDA
IDA: Inferred from direct assay
10748465 MGI
acts upstream of or within signal transduction involved in regulation of gene expression IDA
IDA: Inferred from direct assay
18462699 MGI
involved in ureteric bud development IMP
IMP: Inferred from mutant phenotype
22114682 MGI
Cellular Component GO Annotation Evidence Reference Source
located in extracellular region IDA
IDA: Inferred from direct assay
9431803 MGI
located in extracellular space IDA
IDA: Inferred from direct assay
10748465 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cerberus

cer-l

cerberus 1 homolog

cerberus homolog

cerberus-like protein

cerberus-related protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (9)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-126015 P053 Inhibitor ≥97.0% Unkown
HY-120803 Mefluidide 99.81% Unkown
HY-146910S CER1 (d18:1/26:0/18:1)-d9 ≥99.0% Unkown
HY-RS02532 CER1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS02536 CERS1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS18128 Cer1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS19995 Cers1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24602 Cer1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26499 Cers1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cer1 NCBI NCBI:9350