1. Gene
  2. Birc6 - baculoviral IAP repeat-containing 6 Gene

Birc6 - baculoviral IAP repeat-containing 6 Gene

Mus musculus

Also known as Bruce; mKIAA1289; A430032G04Rik; A430040A19Rik; D630005A10Rik

Gene ID: 12211 | Gene type: protein coding

About Birc6

Summary

Enables ubiquitin conjugating enzyme activity. Involved in placenta development. Acts upstream of or within embryonic placenta development; negative regulation of apoptotic process; and positive regulation of cell population proliferation. Located in membrane. Is expressed in several structures, including genitourinary system; heart; liver; lung; and spleen. Orthologous to human BIRC6 (baculoviral IAP repeat containing 6). [provided by Alliance of Genome Resources, Apr 2022]

Birc6 Products(2)

mRNA Protein Name
NM_001402769.1 NP_001389698.1 baculoviral IAP repeat-containing protein 6 isoform 2
NM_007566.3 NP_031592.3 baculoviral IAP repeat-containing protein 6
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
15314180 MGI
enables ubiquitin conjugating enzyme activity IDA
IDA: Inferred from direct assay
9628897 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of cell population proliferation IMP
IMP: Inferred from mutant phenotype
15887267 MGI
acts upstream of or within labyrinthine layer development IMP
IMP: Inferred from mutant phenotype
15485903 MGI
acts upstream of or within negative regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
15300255 MGI
involved in placenta development IMP
IMP: Inferred from mutant phenotype
15485903 MGI
acts upstream of or within positive regulation of cell population proliferation IMP
IMP: Inferred from mutant phenotype
15887267 MGI
acts upstream of or within regulation of cell population proliferation IMP
IMP: Inferred from mutant phenotype
15485903 MGI
acts upstream of or within spongiotrophoblast layer development IMP
IMP: Inferred from mutant phenotype
15485903 MGI
Cellular Component GO Annotation Evidence Reference Source
located in membrane IDA
IDA: Inferred from direct assay
9628897 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

baculoviral IAP repeat-containing protein 6

BIR repeat-containing ubiquitin-conjugating enzyme

RING-type E3 ubiquitin transferase BIRC6

apollon

baculovirus inhibitor of apoptosis repeat containing ubiquitin-conjugating enzyme

baculovirus inhibitor of apoptosis repeat containing ubiquitin-conjug

Orthologs Information

Species Symbol Source ID
Homo sapiens Birc6 NCBI NCBI:57448