Hnrnpd - heterogeneous nuclear ribonucleoprotein D Gene

Mus musculus

Also known as Auf1; Hnrpd

Gene ID: 11991 | Gene type: protein coding

About Hnrnpd

Summary

Predicted to enable chromatin binding activity; histone deacetylase binding activity; and nucleic acid binding activity. Involved in mRNA transcription by RNA polymerase II and regulation of nucleobase-containing compound metabolic process. Acts upstream of or within regulation of mRNA stability. Located in synapse. Is expressed in several structures, including branchial arch; central nervous system; genitourinary system; gut; and hemolymphoid system gland. Orthologous to human HNRNPD (heterogeneous nuclear ribonucleoprotein D). [provided by Alliance of Genome Resources, Apr 2022]

Hnrnpd Products(8)

mRNA	Protein	Name
NM_001077265.2	NP_001070733.1	heterogeneous nuclear ribonucleoprotein D0 isoform a
NM_001077266.2	NP_001070734.1	heterogeneous nuclear ribonucleoprotein D0 isoform b
NM_001077267.2	NP_001070735.1	heterogeneous nuclear ribonucleoprotein D0 isoform d
NM_007516.3	NP_031542.2	heterogeneous nuclear ribonucleoprotein D0 isoform c
NM_001077265.2	NP_001070733.1	heterogeneous nuclear ribonucleoprotein D0 isoform a
NM_001077266.2	NP_001070734.1	heterogeneous nuclear ribonucleoprotein D0 isoform b
NM_001077267.2	NP_001070735.1	heterogeneous nuclear ribonucleoprotein D0 isoform d
NM_007516.3	NP_031542.2	heterogeneous nuclear ribonucleoprotein D0 isoform c

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	12107167	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of positive regulation of telomere capping	IMP IMP: Inferred from mutant phenotype	22633954	MGI
acts upstream of positive regulation of telomere maintenance via telomerase	IMP IMP: Inferred from mutant phenotype	22633954	MGI
involved in positive regulation of transcription by RNA polymerase II	IMP IMP: Inferred from mutant phenotype	22633954	MGI
acts upstream of or within regulation of mRNA stability	IMP IMP: Inferred from mutant phenotype	14976220	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
is active in synapse	EXP EXP: Inferred from Experiment	16452087	MGI
is active in synapse	IDA IDA: Inferred from direct assay	16452087	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

heterogeneous nuclear ribonucleoprotein D0

AU-rich element RNA-binding protein 1

hnRNP D0

Hnrnpd Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	Hnrnpd	Q60668	Ldha	Mus musculus	P06151	Density Sedimentation	12107167
Intra	Hnrnpd	Q60668	Ldha	Mus musculus	P06151	Anti Bait CoIP	12107167

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-176305S	Neurofilament, U-15N		/	Unkown
HY-RS06267	HNRNPD Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS21865	Hnrnpd Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Hnrnpd	NCBI	NCBI:3184

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