2. Gene
  3. Tpm3 - tropomyosin 3 Gene

Tpm3 - tropomyosin 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Tpm5; TM30nm

Gene ID: 117557 | Gene type: protein coding

About Tpm3

Summary

Predicted to enable actin filament binding activity. Involved in brain development. Located in brush border. Human ortholog(s) of this gene implicated in congenital fiber-type disproportion and nemaline myopathy 1. Orthologous to human TPM3 (tropomyosin 3). [provided by Alliance of Genome Resources, Apr 2022]

Tpm3 Products(4)

mRNA Protein Name
NM_001301285.1 NP_001288214.1 tropomyosin alpha-3 chain isoform Tpm3.12st
NM_001301286.1 NP_001288215.1 tropomyosin alpha-3 chain isoform Tpm3.3cy
NM_057208.2 NP_476556.2 tropomyosin alpha-3 chain isoform Tpm3.4cy
NM_173111.2 NP_775134.2 tropomyosin alpha-3 chain isoform Tpm3.1cy
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
located in brush border IDA
IDA: Inferred from direct assay
22114352 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tropomyosin alpha-3 chain

gamma-tropomyosin

nonmuscle tropomyosin 5

tropomyosin 3, gamma

tropomyosin non-muscle

tropomyosin-5

Related Agents

Pre-clinical Phase
Bioactive Molecules (8)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-124689 TR-100 Inhibitor ≥99.0% Unkown
HY-137465 CG428 Degrader 98.26% Unkown
HY-131244 ALK-IN-9 Inhibitor / Unkown
HY-157542 CG428-NEG Control / Unkown
HY-RS14938 TPM3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-164514 NMS-P626 Inhibitor / Unkown
HY-RS18503 Tpm3 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24985 Tpm3 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tpm3 NCBI NCBI:7170