Acacb - acetyl-CoA carboxylase beta Gene

Rattus norvegicus

Also known as Acc2

Gene ID: 116719 | Gene type: protein coding

About Acacb

Summary

Enables biotin binding activity. Involved in response to organic cyclic compound and response to xenobiotic stimulus. Located in mitochondrion. Used to study fatty liver disease. Orthologous to human ACACB (Acetyl-CoA Carboxylase beta). [provided by Alliance of Genome Resources, Apr 2022]

Acacb Products(1)

mRNA	Protein	Name
NM_053922.2	NP_446374.2	acetyl-CoA carboxylase 2 precursor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables biotin binding	IDA IDA: Inferred from direct assay	12949377	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in D-glucose import	IMP IMP: Inferred from mutant phenotype	31709908	RGD
involved in fatty acid oxidation	IMP IMP: Inferred from mutant phenotype	31709908	RGD
involved in intracellular aspartate homeostasis	IMP IMP: Inferred from mutant phenotype	31709908	RGD
involved in intracellular glutamate homeostasis	IMP IMP: Inferred from mutant phenotype	31709908	RGD
involved in lactic acid secretion	IMP IMP: Inferred from mutant phenotype	31709908	RGD
involved in pentose-phosphate shunt	IMP IMP: Inferred from mutant phenotype	31709908	RGD
involved in purine nucleotide metabolic process	IMP IMP: Inferred from mutant phenotype	31709908	RGD
involved in regulation of cardiac muscle hypertrophy in response to stress	IMP IMP: Inferred from mutant phenotype	31709908	RGD
involved in response to nutrient	IEP IEP: Inferred from expression pattern	26394137	RGD
involved in response to nutrient levels	IEP IEP: Inferred from expression pattern	25943649	RGD
involved in response to organic cyclic compound	IMP IMP: Inferred from mutant phenotype	12842871	RGD
involved in response to xenobiotic stimulus	IEP IEP: Inferred from expression pattern	16979414	RGD
involved in tricarboxylic acid metabolic process	IMP IMP: Inferred from mutant phenotype	31709908	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
part of mitochondrial fatty acid beta-oxidation multienzyme complex	IDA IDA: Inferred from direct assay	31709908	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

acetyl-CoA carboxylase 2

acetyl-Coenzyme A carboxylase 2

acetyl-Coenzyme A carboxylase beta

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00122	ACACB Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS20357	Acacb Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS26866	Acacb Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Acacb	NCBI	NCBI:32

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