2. Gene
  3. Bik - BCL2-interacting killer Gene

Bik - BCL2-interacting killer Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Blk; Biklk

Gene ID: 114496 | Gene type: protein coding

About Bik

Summary

Enables BH domain binding activity. Predicted to be involved in apoptotic mitochondrial changes; male gonad development; and positive regulation of cellular component organization. Predicted to act upstream of or within spermatogenesis. Predicted to be located in mitochondrial envelope. Human ortholog(s) of this gene implicated in ataxia telangiectasia; breast cancer; colon cancer; and prostate Cancer. Orthologous to human BIK (BCL2 interacting killer). [provided by Alliance of Genome Resources, Apr 2022]

Bik Products(1)

mRNA Protein Name
NM_053704.2 NP_446156.1 bcl-2-interacting killer
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables BH domain binding IPI
IPI: Inferred from physical interaction
9356461 RGD
enables protein-containing complex binding IPI
IPI: Inferred from physical interaction
9356461 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

bcl-2-interacting killer

BCL2-interacting killer (apoptosis-inducing)

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-50868 Bafetinib 99.18% Phase 2
Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P5341 Bik BH3 / Unkown
HY-RS01503 BIK Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS17788 Bik Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24255 Bik Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Bik NCBI NCBI:638
Mus musculus Bik NCBI NCBI:12124