1. Gene
  2. Phyh - phytanoyl-CoA 2-hydroxylase Gene

Phyh - phytanoyl-CoA 2-hydroxylase Gene

Rattus norvegicus
Gene ID: 114209 | Gene type: protein coding

About Phyh

Summary

Enables phytanoyl-CoA dioxygenase activity. Involved in 2-oxobutyrate catabolic process and fatty acid alpha-oxidation. Located in mitochondrion and peroxisome. Biomarker of non-alcoholic fatty liver disease. Human ortholog(s) of this gene implicated in Refsum disease; Zellweger syndrome; orofacial cleft; and peroxisomal disease. Orthologous to human PHYH (phytanoyl-CoA 2-hydroxylase). [provided by Alliance of Genome Resources, Apr 2022]

Phyh Products(1)

mRNA Protein Name
NM_053674.2 NP_446126.1 phytanoyl-CoA dioxygenase, peroxisomal precursor
Protein Preferred Names Protein Names

phytanoyl-CoA dioxygenase, peroxisomal

phytanic acid oxidase

phytanoyl-CoA alpha-hydroxylase

phytanoyl-CoA hydroxylase (Refsum disease)

Orthologs Information

Species Symbol Source ID
Homo sapiens Phyh NCBI NCBI:5264