2. Gene
  3. Abcb7 - ATP-binding cassette, sub-family B (MDR/TAP), member 7 Gene

Abcb7 - ATP-binding cassette, sub-family B (MDR/TAP), member 7 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Abc7

Gene ID: 11306 | Gene type: protein coding

About Abcb7

Summary

Predicted to enable ABC-type iron-sulfur cluster transporter activity and protein homodimerization activity. Involved in iron-sulfur cluster assembly; positive regulation of heme biosynthetic process; and positive regulation of iron-sulfur cluster assembly. Acts upstream of or within cellular iron ion homeostasis. Located in mitochondrial inner membrane. Is expressed in several structures, including adrenal gland; central nervous system; gut; hemolymphoid system gland; and retina. Human ortholog(s) of this gene implicated in X-linked sideroblastic anemia with ataxia. Orthologous to human ABCB7 (ATP binding cassette subfamily B member 7). [provided by Alliance of Genome Resources, Apr 2022]

Abcb7 Products(1)

mRNA Protein Name
NM_009592.1 NP_033722.1 iron-sulfur clusters transporter ABCB7, mitochondrial
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
30765471 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within intracellular iron ion homeostasis IMP
IMP: Inferred from mutant phenotype
16424901 MGI
involved in intracellular iron ion homeostasis IMP
IMP: Inferred from mutant phenotype
30765471 MGI
involved in iron-sulfur cluster assembly IMP
IMP: Inferred from mutant phenotype
30765471 MGI
involved in positive regulation of heme biosynthetic process IMP
IMP: Inferred from mutant phenotype
30765471 MGI
involved in positive regulation of iron-sulfur cluster assembly IMP
IMP: Inferred from mutant phenotype
16467350 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

iron-sulfur clusters transporter ABCB7, mitochondrial

ABC transporter 7 protein

ATP-binding cassette 7

ATP-binding cassette sub-family B member 7, mitochondrial

ATP-binding cassette transporter 7

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00054 ABCB7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21467 Abcb7 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27985 Abcb7 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Abcb7 NCBI NCBI:22