2. Gene
  3. Abca1 - ATP-binding cassette, sub-family A (ABC1), member 1 Gene

Abca1 - ATP-binding cassette, sub-family A (ABC1), member 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Abc1; ABC-1

Gene ID: 11303 | Gene type: protein coding

About Abca1

Summary

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. In humans, this protein functions as a Cholesterol efflux pump in the cellular lipid removal pathway. Mutations in the human gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency. [provided by RefSeq, Jul 2008]

Abca1 Products(2)

mRNA Protein Name
NM_013454.3 NP_038482.3 phospholipid-transporting ATPase ABCA1
NM_013454.3 NP_038482.3 phospholipid-transporting ATPase ABCA1
Protein Preferred Names Protein Names

phospholipid-transporting ATPase ABCA1

ATP-binding cassette 1

ATP-binding cassette sub-family A member 1

ATP-binding cassette transporter 1

Related Agents

Approval
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B0388 Probucol 99.97% Yes
Clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-134377 Bocidelpar Modulator 98.08% Phase 2
HY-P6306A CS-6253 TFA 98.53% Phase 1
Pre-clinical Phase
Bioactive Molecules (25)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-D0086 DIDS sodium salt Inhibitor 99.13% Unkown
HY-P6306 CS-6253 98.84% Unkown
HY-123402 GSK3987 Agonist 99.19% Unkown
HY-N2419 Erythrodiol 99.75% Unkown
HY-18282 AZ876 Agonist 99.77% Unkown
HY-N0686 Pseudoprotodioscin Inhibitor 99.17% Unkown
HY-123148 IMB-808 Agonist 99.85% Unkown
HY-143200 OSBPL7-IN-1 Inhibitor 99.84% Unkown
HY-141645 IMM-H007 97.69% Unkown
HY-N0364 Falcarindiol 99.48% Unkown
HY-117006 E1231 Activator 98.46% Unkown
HY-122936 Tanshindiol C 98.47% Unkown
HY-NP203 High density lipoprotein (human) Activator ≥98% Unkown
HY-RS00037 ABCA1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W590664 C2 Dihydroceramide / Unkown
HY-121671 TBTC Activator / Unkown
HY-121693 DIDS Inhibitor / Unkown
HY-169080 ABCA1 inducer 1 Inducer / Unkown
HY-170570 PFM046 / Unkown
HY-173230 ABCA1 inducer 2 / Unkown
HY-N13361 Elodeoidileon A Agonist / Unkown
HY-W201317 E17241 Agonist / Unkown
HY-W674245 10-Hydroxyhexadecanoic acid / Unkown
HY-RS16554 Abca1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22987 Abca1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Abca1 NCBI NCBI:19