2. Gene
  3. Npy - neuropeptide Y Gene

Npy - neuropeptide Y Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 0710005A05Rik

Gene ID: 109648 | Gene type: protein coding

About Npy

Summary

This gene encodes a neuropeptide that plays a pivotal role in many physiological functions such as food intake, energy homeostasis, circadian rhythm, and cognition. The encoded protein precursor undergoes proteolytic processing to generate the biologically active peptide. Mice lacking the encoded protein exhibit mild seizures occasionally and become hyperphagic following food deprivation. A deficiency of the encoded protein partially prevents mice lacking Leptin from becoming obese. [provided by RefSeq, Oct 2015]

Npy Products(1)

mRNA Protein Name
NM_023456.3 NP_075945.1 pro-neuropeptide Y preproprotein
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables G protein-coupled receptor binding IDA
IDA: Inferred from direct assay
10698177 MGI
enables G protein-coupled receptor binding IGI
IGI: Inferred from genetic interaction
9623984 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within regulation of blood pressure IDA
IDA: Inferred from direct assay
9623984 MGI
involved in synaptic signaling via neuropeptide EXP
EXP: Inferred from Experiment
22190627 MGI
involved in synaptic signaling via neuropeptide IDA
IDA: Inferred from direct assay
22190627 MGI
Cellular Component GO Annotation Evidence Reference Source
is active in GABA-ergic synapse EXP
EXP: Inferred from Experiment
22190627 MGI
is active in GABA-ergic synapse IDA
IDA: Inferred from direct assay
22190627 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
24582971 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

pro-neuropeptide Y

Related Agents

Clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-14423 Velneperit Antagonist 99.21% Phase 2
HY-P10026 Nisotirostide Agonist 99.45% Phase 1
Pre-clinical Phase
Bioactive Molecules (64)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-107725 BIBO3304 Antagonist 99.95% Unkown
HY-101986 BIIE-0246 Antagonist 99.10% Unkown
HY-116797 MS15203 99.51% Unkown
HY-107726 BIBP3226 TFA Antagonist 99.25% Unkown
HY-P10000 Peptide YY (PYY) (3-36), Human Agonist 98.57% Unkown
HY-P0208 [Leu31,Pro34]-Neuropeptide Y (porcine) Agonist 98.40% Unkown
HY-P1845 PACAP-38 (31-38), human, mouse, rat Inducer 99.98% Unkown
HY-P1845A PACAP-38 (31-38), human, mouse, rat TFA Inducer 98.33% Unkown
HY-107565 2-Pyridylethylamine hydrochloride Agonist 99.86% Unkown
HY-120619 BMS-193885 Antagonist 99.08% Unkown
HY-P2543 Neuropeptide Y (3-36) (human, rat) Agonist 95.78% Unkown
HY-107734 L 152804 Antagonist 99.89% Unkown
HY-P0199 Pancreatic Polypeptide, human Agonist 99.82% Unkown
HY-P4060A Pancreatic polypeptide TFA Agonist 99.47% Unkown
HY-101986A BIIE-0246 hydrochloride Antagonist ≥99.0% Unkown
HY-107733 NTNCB hydrochloride Antagonist 98.36% Unkown
HY-107735 CYM 9484 Antagonist 99.43% Unkown
HY-P1011 Neuropeptide Y (13-36), porcine Agonist 99.79% Unkown
HY-P10148 N-Acetyl [Leu28, Leu31] neuropeptide Y (24–36) Agonist 98.03% Unkown
HY-P1324 [cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide Agonist 99.25% Unkown
HY-W141779 Boc-Cys(Npys)-OH ≥98.0% Unkown
HY-107728 S 25585 Antagonist 99.13% Unkown
HY-107730 NPY5RA-972 Antagonist 98.86% Unkown
HY-148179 Neuropeptide Y5 receptor ligand-1 Antagonist ≥98.0% Unkown
HY-P1322 [D-Trp34]-Neuropeptide Y Agonist 98.58% Unkown
HY-P3678 Neuropeptide Y (18-36) (porcine) Antagonist 98.76% Unkown
HY-156922 NPY-5 receptor antagonist-1 Antagonist 99.86% Unkown
HY-RS09511 NPY1R Human Pre-designed siRNA Set A / Unkown
HY-107726A BIBP3226 Antagonist / Unkown
HY-101986C BIIE-0246 dihydrochloride Antagonist / Unkown
HY-103247 EMD 66684 Antagonist / Unkown
HY-107723A CGP71683 Antagonist / Unkown
HY-107725A BIBO3304 diTFA Inhibitor / Unkown
HY-110107 GW438014A Antagonist 99.98% Unkown
HY-118198 NPY Y2 antagonist 1 Antagonist / Unkown
HY-120096 BIBO3304 free base Antagonist / Unkown
HY-P0198B [D-Arg25]-Neuropeptide Y (human) Agonist / Unkown
HY-P10291 [Pro34]Neuropeptide Y, porcine Agonist / Unkown
HY-P10545 [D-His26]-Neuropeptide Y, human, rat Agonist / Unkown
HY-P1322A [D-Trp34]-Neuropeptide Y TFA Agonist / Unkown
HY-P1324A [cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic polypeptide TFA Agonist / Unkown
HY-P1532 Pancreatic Polypeptide, rat Agonist / Unkown
HY-P1537 Pancreatic Polypeptide, bovine Agonist / Unkown
HY-P1817 PACAP-38 (16-38), human, mouse, rat / Unkown
HY-P3676 Neuropeptide Y (3-36) (porcine) Agonist / Unkown
HY-P3679 Neuropeptide Y (1-24) (human) Activator / Unkown
HY-P4101 Cys(Npys)-TAT (47-57) / Unkown
HY-P4103 Cys(Npys)-TAT (47-57), FAM-labeled / Unkown
HY-P4123 TAT (47-57) GGG-Cys(Npys) / Unkown
HY-RS09510 NPY Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS09512 Npy1r Mouse Pre-designed siRNA Set A / Unkown
HY-RS09513 Npy1r Rat Pre-designed siRNA Set A / Unkown
HY-RS09514 NPY2R Human Pre-designed siRNA Set A / Unkown
HY-RS09515 Npy2r Mouse Pre-designed siRNA Set A / Unkown
HY-RS09516 NPY2R Rat Pre-designed siRNA Set A / Unkown
HY-RS09517 NPY4R Human Pre-designed siRNA Set A / Unkown
HY-RS09518 Npy4r Mouse Pre-designed siRNA Set A / Unkown
HY-RS09519 Npy4r Rat Pre-designed siRNA Set A / Unkown
HY-RS09520 NPY5R Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS09521 Npy5r Mouse Pre-designed siRNA Set A / Unkown
HY-RS09522 Npy5r Rat Pre-designed siRNA Set A / Unkown
HY-RS16546 Npy Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS22978 Npy Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-W336281 Fmoc-Cys(npys)-OH / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Npy NCBI NCBI:4852