2. Gene
  3. Mbd5 - methyl-CpG binding domain protein 5 Gene

Mbd5 - methyl-CpG binding domain protein 5 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Gm1630; 9430004D19Rik; C030040A15Rik

Gene ID: 109241 | Gene type: protein coding

About Mbd5

Summary

Predicted to enable chromatin binding activity. Acts upstream of or within glucose homeostasis; positive regulation of growth hormone receptor signaling pathway; and regulation of growth. Predicted to be located in midbody and nucleoplasm. Predicted to be active in chromocenter and nucleus. Is expressed in several structures, including brain; liver; small intestine; spinal cord; and spleen. Used to study autosomal dominant non-syndromic intellectual disability. Human ortholog(s) of this gene implicated in autism spectrum disorder and autosomal dominant non-syndromic intellectual disability 1. Orthologous to human MBD5 (methyl-CpG binding domain protein 5). [provided by Alliance of Genome Resources, Apr 2022]

Mbd5 Products(2)

mRNA Protein Name
NM_001290656.1 NP_001277585.1 methyl-CpG-binding domain protein 5 isoform b
NM_029924.2 NP_084200.1 methyl-CpG-binding domain protein 5 isoform a
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within glucose homeostasis IMP
IMP: Inferred from mutant phenotype
23077600 MGI
acts upstream of or within positive regulation of growth hormone receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
23077600 MGI
acts upstream of or within regulation of multicellular organism growth IMP
IMP: Inferred from mutant phenotype
23077600 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

methyl-CpG-binding domain protein 5

methyl-CpG-binding protein MBD5

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08185 MBD5 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS22229 Mbd5 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mbd5 NCBI NCBI:55777