Cavin3 - caveolae associated 3 Gene

Mus musculus

Also known as SRBC; Prkcdbp; 3110015B12Rik; 6330514M23Rik

Gene ID: 109042 | Gene type: protein coding

About Cavin3

Summary

Enables protein kinase C binding activity. Involved in circadian regulation of gene expression. Acts upstream of or within cortical actin Cytoskeleton organization; negative regulation of fermentation; and regulation of intracellular signal transduction. Located in caveola and cytoplasm. Is expressed in several structures, including brain; genitourinary system; gut; integumental system; and quadriceps femoris muscle. Orthologous to human CAVIN3 (caveolae associated protein 3). [provided by Alliance of Genome Resources, Apr 2022]

Cavin3 Products(1)

mRNA	Protein	Name
NM_028444.1	NP_082720.1	caveolae-associated protein 3

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	23079727	MGI
enables protein kinase C binding	IPI IPI: Inferred from physical interaction	9857183	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in circadian regulation of gene expression	IMP IMP: Inferred from mutant phenotype	23079727	MGI
acts upstream of or within cortical actin cytoskeleton organization	IMP IMP: Inferred from mutant phenotype	24069528	MGI
acts upstream of or within negative regulation of fermentation	IMP IMP: Inferred from mutant phenotype	24069528	MGI
acts upstream of or within negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	IMP IMP: Inferred from mutant phenotype	24069528	MGI
acts upstream of or within positive regulation of ERK1 and ERK2 cascade	IMP IMP: Inferred from mutant phenotype	24069528	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in caveola	IDA IDA: Inferred from direct assay	25588833	MGI
located in cytoplasm	IDA IDA: Inferred from direct assay	23079727	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

caveolae-associated protein 3

cavin-3	protein kinase C, delta binding protein
serum deprivation response factor-related gene product that binds to C-kinase

Cavin3 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	Cavin3	Q91VJ2	Per2	Mus musculus	O54943	Anti Tag CoIP	23079727
Intra	Cavin3	Q91VJ2	Per2	Mus musculus	O54943	IF	23079727

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01990	CAVIN3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS21833	Cavin3 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Cavin3	NCBI	NCBI:112464

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