2. Gene
  3. Atf5 - activating transcription factor 5 Gene

Atf5 - activating transcription factor 5 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as AFTA; Atf7; Atfx; ODA-10

Gene ID: 107503 | Gene type: protein coding

About Atf5

Summary

Enables chromatin binding activity and transcription cis-regulatory region binding activity. Involved in cerebellar granule cell precursor proliferation and fat cell differentiation. Acts upstream of or within several processes, including circadian rhythm; negative regulation of apoptotic process; and olfactory bulb interneuron development. Located in nucleus. Part of transcription regulator complex. Is expressed in several structures, including alimentary system; central nervous system; integumental system; sensory organ; and urinary system. Orthologous to human ATF5 (activating transcription factor 5). [provided by Alliance of Genome Resources, Apr 2022]

Atf5 Products(1)

mRNA Protein Name
NM_030693.2 NP_109618.1 cyclic AMP-dependent transcription factor ATF-5
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables chromatin binding IDA
IDA: Inferred from direct assay
24216764 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
22974638 MGI
enables sequence-specific DNA binding IDA
IDA: Inferred from direct assay
24216764 MGI
enables transcription cis-regulatory region binding IDA
IDA: Inferred from direct assay
24216764 MGI
Biological Process GO Annotation Evidence Reference Source
involved in cerebellar granule cell precursor proliferation IMP
IMP: Inferred from mutant phenotype
22095825 MGI
involved in circadian rhythm IEP
IEP: Inferred from expression pattern
21768648 MGI
involved in fat cell differentiation IMP
IMP: Inferred from mutant phenotype
24216764 MGI
acts upstream of or within multicellular organism growth IMP
IMP: Inferred from mutant phenotype
23090999 MGI
acts upstream of or within negative regulation of apoptotic process IDA
IDA: Inferred from direct assay
12130540 MGI
acts upstream of or within olfactory bulb interneuron development IMP
IMP: Inferred from mutant phenotype
23090999 MGI
acts upstream of or within olfactory bulb interneuron differentiation IMP
IMP: Inferred from mutant phenotype
23090999 MGI
acts upstream of or within olfactory lobe development IMP
IMP: Inferred from mutant phenotype
23090999 MGI
acts upstream of or within post-embryonic development IMP
IMP: Inferred from mutant phenotype
23090999 MGI
NOT acts upstream of or within regulation of cell cycle IDA
IDA: Inferred from direct assay
12130540 MGI
NOT acts upstream of or within regulation of cell population proliferation IDA
IDA: Inferred from direct assay
12130540 MGI
acts upstream of or within regulation of gene expression IMP
IMP: Inferred from mutant phenotype
23090999 MGI
acts upstream of or within regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
10777215 MGI
Cellular Component GO Annotation Evidence Reference Source
located in nucleus IDA
IDA: Inferred from direct assay
22095825 MGI
part of transcription regulator complex IDA
IDA: Inferred from direct assay
10777215 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cyclic AMP-dependent transcription factor ATF-5

BZIP protein ATF7

NAP1

NRIF3-associated protein

activating transcription factor 5-alpha/beta

activating transcription factor 7

activating transcription factor X

cAMP-dependent transcription factor ATF-5

transcription factor ATFx

transcription fact

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-112680A Carboxy pyridostatin trifluoroacetate salt 99.13% Unkown
HY-RS01131 ATF5 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-112680 Carboxypyridostatin / Unkown
HY-RS19118 Atf5 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25608 Atf5 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Atf5 NCBI NCBI:22809