2. Gene
  3. Txndc5 - thioredoxin domain containing 5 Gene

Txndc5 - thioredoxin domain containing 5 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as ERp46; PC-TRP

Gene ID: 105245 | Gene type: protein coding

About Txndc5

Summary

Predicted to enable protein disulfide isomerase activity. Predicted to be involved in apoptotic cell clearance. Located in endoplasmic reticulum lumen. Is expressed in several structures, including brain; immune system; intestine; male reproductive gland or organ; and urinary system. Orthologous to human TXNDC5 (thioredoxin domain containing 5). [provided by Alliance of Genome Resources, Apr 2022]

Txndc5 Products(3)

mRNA Protein Name
NM_001289598.1 NP_001276527.1 thioredoxin domain-containing protein 5 isoform 2
NM_001289599.1 NP_001276528.1 thioredoxin domain-containing protein 5 isoform 3
NM_145367.4 NP_663342.3 thioredoxin domain-containing protein 5 isoform 1 precursor
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein disulfide isomerase activity IGI
IGI: Inferred from genetic interaction
12930873 MGI
enables protein-disulfide reductase activity IDA
IDA: Inferred from direct assay
14971039 MGI
Cellular Component GO Annotation Evidence Reference Source
located in endoplasmic reticulum lumen IDA
IDA: Inferred from direct assay
12930873 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

thioredoxin domain-containing protein 5

ER protein 46

endoplasmic reticulum protein ERp46

endoplasmic reticulum resident protein 46

plasma cell-specific thioredoxin-related protein

thioredoxin-like protein p46

Related Agents

Pre-clinical Phase
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-122895 E64FC26 98.48% Unkown
HY-112056 DIM-C-pPhCO2Me 99.47% Unkown
HY-122895A (E/Z)-E64FC26 98.09% Unkown
HY-RS15294 TXNDC5 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS17353 Txndc5 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS23807 Txndc5 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Txndc5 NCBI NCBI:81567