2. Gene
  3. Fancm - Fanconi anemia, complementation group M Gene

Fancm - Fanconi anemia, complementation group M Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as D12Ertd364e; C730036B14Rik

Gene ID: 104806 | Gene type: protein coding

About Fancm

Summary

Predicted to enable DNA helicase activity; chromatin binding activity; and four-way junction DNA binding activity. Predicted to be involved in DNA metabolic process and positive regulation of protein monoubiquitination. Predicted to act upstream of or within cellular response to DNA damage stimulus. Predicted to be located in nucleoplasm. Predicted to be part of FANCM-MHF complex and Fanconi anaemia nuclear complex. Is expressed in lung; mandible; and temporal bone petrous part. Human ortholog(s) of this gene implicated in primary ovarian insufficiency 15 and spermatogenic failure 28. Orthologous to human FANCM (FA complementation group M). [provided by Alliance of Genome Resources, Apr 2022]

Fancm Products(2)

mRNA Protein Name
NM_001364447.1 NP_001351376.1 Fanconi anemia group M protein homolog isoform 2
NM_178912.4 NP_849243.2 Fanconi anemia group M protein homolog isoform 1
Protein Preferred Names Protein Names

Fanconi anemia group M protein homolog

ATP-dependent RNA helicase FANCM

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-124325 PIP-199 ≥98.0% Unkown
HY-163573 FANCM-BTR PPI-IN-1 98.61% Unkown
HY-RS04741 FANCM Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS18278 Fancm Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24756 Fancm Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fancm NCBI NCBI:57697